Bglap - bone gamma-carboxyglutamate protein Gene

Rattus norvegicus

Also known as Bgp; Bgpr; Bgpra; Bglap2

Gene ID: 25295 | Gene type: protein coding

About Bglap

Summary

A structural constituent of bone. Involved in several processes, including osteoblast development; response to hydroxyisoflavone; and response to vitamin. Located in several cellular components, including Golgi apparatus; perikaryon; and rough endoplasmic reticulum. Used to study congenital hypothyroidism and osteoporosis. Biomarker of autosomal dominant hypocalcemia; end stage renal disease; and polycystic kidney disease. Human ortholog(s) of this gene implicated in osteoarthritis; osteoporosis; prostate cancer; rheumatoid arthritis; and vitamin K deficiency bleeding. Orthologous to human BGLAP (bone gamma-carboxyglutamate protein). [provided by Alliance of Genome Resources, Apr 2022]

Bglap Products(1)

mRNA	Protein	Name
NM_013414.1	NP_038200.1	osteocalcin preproprotein

Protein Preferred Names

Protein Names

osteocalcin

bone Gla-protein	bone gamma-carboxyglutamate (gla) protein (osteocalcin)
bone gamma-carboxyglutamate protein 2	bone gamma-carboxyglutamic acid (Gla) protein (osteocalcin)
gamma-carboxyglutamic acid-containing protein

Recombinant Bglap Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72104	BGLAP Protein, Rat (GST)	P04640 (Y50-V99)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01488	BGLAP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Bglap	NCBI	NCBI:632
Mus musculus	Bglap	NCBI	NCBI:12096

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