2. Gene
  3. Fgf1 - fibroblast growth factor 1 Gene

Fgf1 - fibroblast growth factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as FGF-1; Fgf2b; HBGF1; HBGF-1

Gene ID: 25317 | Gene type: protein coding

About Fgf1

Summary

Enables HSP70 protein binding activity and growth factor activity. Involved in positive regulation of hepatocyte proliferation. Located in cytoplasm and nucleolus. Used to study brain ischemia. Human ortholog(s) of this gene implicated in brain ischemia; cleft lip; myocardial infarction; schizophrenia; and urinary bladder Cancer. Orthologous to human FGF1 (Fibroblast Growth Factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Fgf1 Products(1)

mRNA Protein Name
NM_012846.2 NP_036978.1 fibroblast growth factor 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables Hsp70 protein binding IPI
IPI: Inferred from physical interaction
10510314 RGD
enables growth factor activity IDA
IDA: Inferred from direct assay
10890892 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of hepatocyte proliferation IDA
IDA: Inferred from direct assay
16756958 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 1

Fibroblast growth factor 1 (heparin binding)

aFGF

acidic fibroblast growth factor

fibroblast growth factor 1 (acidic)

fibroblast growth factor 2b

heparin-binding growth factor 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100434 PD-161570 Inhibitor 99.82% Unkown
HY-149352 DG1 Inhibitor / Unkown
HY-RS04886 FGF1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf1 NCBI NCBI:2246
Canis familiaris Fgf1 NCBI NCBI:607724
Macaca fascicularis Fgf1 NCBI NCBI:102134593
Mus musculus Fgf1 NCBI NCBI:14164