2. Gene
  3. Fgf1 - fibroblast growth factor 1 Gene

Fgf1 - fibroblast growth factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Fam; Fgfa; Dffrx; Fgf-1; Fgf2b

Gene ID: 14164 | Gene type: protein coding

About Fgf1

Summary

Predicted to enable several functions, including HSP70 protein binding activity; S100 protein binding activity; and signaling receptor binding activity. Acts upstream of or within several processes, including organ induction; positive regulation of epithelial cell proliferation; and positive regulation of nitrogen compound metabolic process. Located in extracellular matrix and extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in brain ischemia; cleft lip; myocardial infarction; schizophrenia; and urinary bladder Cancer. Orthologous to human FGF1 (Fibroblast Growth Factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Fgf1 Products(1)

mRNA Protein Name
NM_010197.3 NP_034327.1 fibroblast growth factor 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16263090 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of epithelial cell proliferation IDA
IDA: Inferred from direct assay
17187775 MGI
acts upstream of or within lung development IDA
IDA: Inferred from direct assay
15576401 MGI
acts upstream of or within organ induction IDA
IDA: Inferred from direct assay
15576401 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IDA
IDA: Inferred from direct assay
17187775 MGI
acts upstream of or within positive regulation of protein phosphorylation IDA
IDA: Inferred from direct assay
15800000 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
8898217 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
15381701 MGI
located in extracellular region IDA
IDA: Inferred from direct assay
19233122 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
15576401 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 1

HBGF-1

aFGF

acidic fibroblast growth factor

fibroblast growth factor 1 (acidic)

fibroblast growth factor 2b

heparin-binding growth factor 1

Recombinant Fgf1 Proteins

Cat. No. Product Name Accession Purity
HY-P7065 FGF-1 Protein, Mouse P61148 (F16-D155) ≥95%
HY-P700282 FGF-1 Protein, Mouse (N-His) P61148 (F16-D155) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100434 PD-161570 Inhibitor 99.82% Unkown
HY-149352 DG1 Inhibitor / Unkown
HY-RS04886 FGF1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf1 NCBI NCBI:2246
Canis familiaris Fgf1 NCBI NCBI:607724
Macaca fascicularis Fgf1 NCBI NCBI:102134593
Rattus norvegicus Fgf1 NCBI NCBI:25317