2. Gene
  3. Ptgds - prostaglandin D2 synthase Gene

Ptgds - prostaglandin D2 synthase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as PH2DISO

Gene ID: 25526 | Gene type: protein coding

About Ptgds

Summary

Enables prostaglandin-D synthase activity and retinoid binding activity. Involved in prostaglandin biosynthetic process and response to glucocorticoid. Located in Golgi apparatus and extracellular space. Biomarker of sensorineural hearing loss and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to human PTGDS (prostaglandin D2 synthase). [provided by Alliance of Genome Resources, Apr 2022]

Ptgds Products(1)

mRNA Protein Name
NM_013015.2 NP_037147.1 prostaglandin-H2 D-isomerase precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables prostaglandin-D synthase activity IDA
IDA: Inferred from direct assay
7836410 RGD
enables retinoid binding IDA
IDA: Inferred from direct assay
9188476 RGD
Biological Process GO Annotation Evidence Reference Source
involved in prostaglandin biosynthetic process IDA
IDA: Inferred from direct assay
7836410 RGD
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
14618091 RGD
Cellular Component GO Annotation Evidence Reference Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
11058225 RGD
located in extracellular region IDA
IDA: Inferred from direct assay
8815894 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
17259069 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prostaglandin-H2 D-isomerase

PGD2 synthase

PGDS

PGDS2

Prostaglandin D synthase

glutathione-independent PGD synthase

glutathione-independent PGD synthetase

lipocalin-type prostaglandin-D synthase

prostaglandin D2 synthase (brain)

Recombinant Ptgds Proteins

Cat. No. Product Name Accession Purity
HY-P73709 PGD2 Synthase/PTGDS Protein, Rat (HEK293, His) P22057/NP_037147.1 (Q25-E189) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11374 PTGDS Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptgds NCBI NCBI:5730
Mus musculus Ptgds NCBI NCBI:19215