2. Gene
  3. RNF144B - ring finger protein 144B Gene

RNF144B - ring finger protein 144B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PIR2; IBRDC2; p53RFP; bA528A10.3

Gene ID: 255488 | Gene type: protein coding

About RNF144B

Cytogenetic location: 6p22.3 Genomic coordinates (GRCh38): 6:18,387,350-18,468,870 (from NCBI)

This gene has 2 transcripts (splice variants), 201 orthologues and 9 paralogues. Broad expression in thyroid (RPKM 30.0), lung (RPKM 13.0) and 20 other tissues.

Summary

Enables ubiquitin-protein transferase activity. Involved in negative regulation of apoptotic process and ubiquitin-dependent protein catabolic process. Located in mitochondrial membrane. [provided by Alliance of Genome Resources, Apr 2022]

RNF144B Products(1)

mRNA Protein Name
NM_182757.4 NP_877434.2 E3 ubiquitin-protein ligase RNF144B
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12853982 GOA
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
12853982 GOA
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
20300062 GOA
involved in ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
12853982 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
20300062 GOA
located in mitochondrial membrane IDA
IDA: Inferred from direct assay
20300062 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RNF144B Protein Structure

IBR

IBR: IBR domain, a half RING-finger domain (103 - 166)

IBR

IBR: IBR domain, a half RING-finger domain (188 - 225)

  • 0
  • 100
  • 200
  • 303 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF144B

IBR domain containing 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12054 RNF144B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta RNF144B VGNC VGNC:104424
Mus musculus RNF144B MGD MGI:2384986
Canis familiaris RNF144B VGNC VGNC:45636
Bos taurus RNF144B VGNC VGNC:34027
Felis catus RNF144B VGNC VGNC:102505
Rattus norvegicus RNF144B RGD RGD:1308856