Plau - plasminogen activator, urokinase Gene

Also known as UPAM

About Plau

Summary

Enables peptidase activity. Involved in several processes, including cellular response to hepatocyte growth factor stimulus; cellular response to staurosporine; and positive regulation of ovulation. Located in extracellular space and membrane. Used to study several diseases, including alcoholic liver cirrhosis; lung disease (multiple); sciatic neuropathy; status epilepticus; and transient cerebral ischemia. Biomarker of brain disease (multiple); end stage renal disease; myocardial infarction; sciatic neuropathy; and thrombosis. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease (multiple); Quebec platelet disorder; end stage renal disease; lung disease (multiple); and mitral valve prolapse. Orthologous to human PLAU (plasminogen activator, urokinase). [provided by Alliance of Genome Resources, Apr 2022]