2. Gene
  3. Selp - selectin P Gene

Selp - selectin P Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as PSELECT

Gene ID: 25651 | Gene type: protein coding

About Selp

Summary

Predicted to enable several functions, including fucose binding activity; heparin binding activity; and lipopolysaccharide binding activity. Involved in several processes, including leukocyte migration; regulation of cellular extravasation; and response to lipopolysaccharide. Located in external side of plasma membrane and extracellular space. Used to study acute necrotizing pancreatitis and anti-basement membrane glomerulonephritis. Biomarker of atherosclerosis; colitis; congestive heart failure; and myocardial infarction. Human ortholog(s) of this gene implicated in atopic dermatitis and myocardial infarction. Orthologous to human SELP (Selectin P). [provided by Alliance of Genome Resources, Apr 2022]

Selp Products(1)

mRNA Protein Name
NM_013114.2 NP_037246.2 P-selectin precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
14963004 RGD
involved in leukocyte migration IMP
IMP: Inferred from mutant phenotype
12377736 RGD
involved in positive regulation of cell adhesion IMP
IMP: Inferred from mutant phenotype
19451746 RGD
involved in regulation of cellular extravasation IMP
IMP: Inferred from mutant phenotype
12081568 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
7520013 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
18095572 RGD
Cellular Component GO Annotation Evidence Reference Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
14963004 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
18471420 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

P-selectin

CD62 antigen-like family member P

GMP-140

LECAM3

PADGEM

granule membrane protein 140

leukocyte-endothelial cell adhesion molecule 3

platelet activation dependent granule-external membrane protein

selectin, platelet

Recombinant Selp Proteins

Cat. No. Product Name Accession Purity
HY-P73385 P-Selectin Protein, Rat (HEK293, Fc) P98106/AAI01920.1 (W42-Q700) ≥95%
HY-P73689 P-Selectin Protein, Rat (HEK293, His) P98106/AAI01920.1 (W42-Q700) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12647 SELP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Selp NCBI NCBI:6403
Macaca fascicularis Selp NCBI NCBI:102141875
Mus musculus Selp NCBI NCBI:20344
Macaca mulatta Selp NCBI NCBI:701277