2. Gene
  3. GUCY2C - Gucy2c guanylate cyclase 2C Gene

GUCY2C - Gucy2c guanylate cyclase 2C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as GCC

Gene ID: 25711 | Gene type: protein coding

About GUCY2C

Summary

Enables Guanylate Cyclase activity and toxic substance binding activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to act upstream of or within regulation of cell population proliferation and response to toxic substance. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in congenital diarrhea 6. Orthologous to human GUCY2C (Guanylate Cyclase 2C). [provided by Alliance of Genome Resources, Apr 2022]

GUCY2C Products(1)

mRNA Protein Name
NM_013170.1 NP_037302.1 guanylyl cyclase C precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables guanylate cyclase activity IDA
IDA: Inferred from direct assay
1701694 RGD
enables toxic substance binding IDA
IDA: Inferred from direct assay
1701694 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanylyl cyclase C

heat-stable enterotoxin receptor

GC-C

Guanylate cyclase 2C (heat stable enterotoxin receptor)

STA receptor

intestinal guanylate cyclase

Recombinant GUCY2C Proteins

Cat. No. Product Name Accession Purity
HY-P71666 GUCY2C/Guanylyl cyclase C Protein, Rat (HEK293, Myc, His) P23897 (S23-Q429) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05921 GUCY2C Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99232 Indusatumab ≥99.0% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens GUCY2C NCBI NCBI:2984
Canis familiaris GUCY2C NCBI NCBI:486671
Macaca fascicularis GUCY2C NCBI NCBI:102130850
Mus musculus GUCY2C NCBI NCBI:14917