TMEM98 - transmembrane protein 98 Gene

Homo sapiens

Also known as TADA1

Gene ID: 26022 | Gene type: protein coding

About TMEM98

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:32,928,153-32,944,315 (from NCBI)

This gene has 9 transcripts (splice variants), 209 orthologues and is associated with 3 phenotypes. Ubiquitous expression in ovary (RPKM 69.4), endometrium (RPKM 44.6) and 23 other tissues.

Summary

This gene encodes a transmembrane protein. A missense mutation in this gene result in Nanophthalmos 4 (NNO4). Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2014]

TMEM98 Products(3)

mRNA	Protein	Name
NM_001033504.2	NP_001028676.1	transmembrane protein 98
NM_001301746.2	NP_001288675.1	transmembrane protein 98
NM_015544.3	NP_056359.2	transmembrane protein 98

TMEM98 Protein Structure

GCIP

0
100
200
226 a.a.

Protein Preferred Names

Protein Names

transmembrane protein 98

Related Diseases

Diseases

Alias

Nanophthalmos 4

NNO4	Nanophthalmia 4
Nanophthalmos, Type 4

Nanophthalmos

Nanophthalmia

Aqueous Misdirection

Interval Angle-Closure Glaucoma

Intermittent Angle-Closure Glaucoma	Angle-Closure Glaucoma, Subacute
Prodromal Angle Closure Glaucoma

Microphthalmia, Isolated 6

Isolated Microphthalmia 6	MCOP6
Microphthalmia, Posterior Nonsyndromic	Posterior Nonsyndromic Microphthalmia
Microphthalmia, Isolated, 6	Autosomal Recessive Posterior Microphthalmos
Posterior Non-Syndromic Microphthalmia	Microphthalmia, Isolated, Type 6

Farsightedness

Hypermetropia	Hyperopia
Far-Sightedness	Farsighted
Long-Sighted	Long-Sightedness

Bullous Retinoschisis

Kenny-Caffey Syndrome

Kenny Syndrome

Optic Disk Drusen

Optic Disc Drusen	Drusen Of Optic Disc
Optic Nerve Head Drusen	Drusen Optic Disc

Kenny-Caffey Syndrome, Type 2

KCS2	Kenny-Caffey Syndrome Type 2
Autosomal Dominant Kenny-Caffey Syndrome	Kenny Syndrome
Dwarfism, Cortical Thickening Of Tubular Bones, And Transient Hypocalcemia	Dwarfism, Cortical Thickening Of Tubular Bones And Transient Hypocalcemia
Kenny-Caffey Syndrome, Autosomal Dominant	Kenny-Caffey Syndrome 2
Dwarfism With Cortical Thickening Of Tubular Bones And Transient Hypocalcemia	Kenny-Caffey Syndrome

Isolated Microphthalmia

Vitreoretinochoroidopathy

Autosomal Dominant Vitreoretinochoroidopathy	Advirc
Vitreoretinochoroidopathy With Microcornea, Glaucoma, And Cataract	Vitreoretinochoroidopathy, Autosomal Dominant, With Nanophthalmos
Microcornea, Rod-Cone Dystrophy, Cataract, And Posterior Staphyloma 2	Vitreoretinochoroidopathy Dominant
VRCP	Vitreoretinochoroidopathy, Autosomal Dominant
Vrcp Autosomal Dominant	Vitreoretinochoroidopathy Autosomal Dominant With Nanophthalmos, Microcornea, Rod-Cone Dystrophy, Cataract And Posterior Staphyloma
Vitreoretinochoroidopathy With Microcornea-Glaucoma-Cataract

Acute Closed-Angle Glaucoma

Acute Angle-Closure Glaucoma

Total Anomalous Pulmonary Venous Return 1

Scimitar Syndrome	Total Anomalous Pulmonary Venous Return
Anomalous Pulmonary Venous Return	Scimitar Anomaly
TAPVR1	Apvr
Halasz Syndrome	Hypogenetic Lung Syndrome
Pulmonary Venolobar Syndrome	TAPVR
Congenital Total Pulmonary Venous Return Anomaly	Congenital Venolobar Syndrome
Mirror-Image Lung Syndrome	Vena Cava Bronchovascular Syndrome
Pulmonary Venous Return Anomaly	Congenital Pulmonary Venolobar Syndrome
Epibronchial Right Pulmonary Vein Syndrome

Diaphragm Disease

Abnormality Of The Diaphragm	Disease Of Diaphragm
Diaphragmatic Disorder	Disorder Of Diaphragm

Primary Angle-Closure Glaucoma

Primary Angle Closure Glaucoma	Angle Closure Glaucoma
Acg - [Angle Closure Glaucoma]	Angle-Closure Glaucoma
Closed Angle Glaucoma	Acute Glaucoma
Prodromal Angle Closure Glaucoma

Diaphragmatic Hernia, Congenital

Congenital Diaphragmatic Hernia	Diaphragmatic Hernia
Cdh	Congenital Diaphragmatic Defect
Hernia, Diaphragmatic	Dih
Hernia, Congenital Diaphragmatic	Hcd
Diaphragmatic Defect, Congenital	Diaphragm, Unilateral Agenesis Of
Hemidiaphragm, Agenesis Of	Diaphragmatic Hernia 1
Agenesis Of Hemidiaphragm	Unilateral Agenesis Of Diaphragm
Hernia Diaphragmatic	Hernia Diaphragmatic Congenital
Hernia, Diaphragmatic, Type 1	Hiatus Hernia
Oesophageal Hiatus Hernia	Paraoesophageal Hernia
Sliding Hiatus Hernia	Congenital Diaphragm Hernia
Congenital Diaphragm Defect With Hernia	Gross Congenital Diaphragm Defect

Kallmann Syndrome

Hypogonadism With Anosmia	Kallman'S Syndrome
Anosmic Hypogonadism	Anosmic Idiopathic Hypogonadotropic Hypogonadism
Hypogonadotropic Hypogonadism And Anosmia	Hypogonadotropic Hypogonadism-Anosmia Syndrome
Olfacto-Genital Pathological Sequence	Familial Hypogonadism With Anosmia
Kallman Syndrome	Dysplasia Olfactogenitalis Of De Morsier
Kallmann'S Syndrome	Congenital Hypogonadotropic Hypogonadism With Anosmia

Refractive Error

Refractive Errors

Fundus Albipunctatus

Retinitis Punctata Albescens	Pigmentary Retinal Dystrophy
RPA	Albipunctate Retinal Dystrophy
Lauber'S Disease	FALBI
Fa

Fundus Dystrophy

Retinal Dystrophy	Retinal Dystrophies
Dystrophy, Retinal

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14753	TMEM98 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TMEM98	RGD	RGD:1359736
Felis catus	TMEM98	VGNC	VGNC:66374
Macaca mulatta	TMEM98	VGNC	VGNC:99306
Mus musculus	TMEM98	MGD	MGI:1923457
Bos taurus	TMEM98	VGNC	VGNC:36130
Canis familiaris	TMEM98	VGNC	VGNC:47618

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