2. Gene
  3. Slc27a1 - solute carrier family 27 (fatty acid transporter), member 1 Gene

Slc27a1 - solute carrier family 27 (fatty acid transporter), member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Fatp; FATP1; Vlc27a1

Gene ID: 26457 | Gene type: protein coding

About Slc27a1

Summary

Enables fatty acid Ligase activity; fatty acid transmembrane transporter activity; and identical protein binding activity. Involved in glucose import in response to Insulin stimulus; long-chain fatty acid import into cell; and positive regulation of triglyceride biosynthetic process. Acts upstream of or within several processes, including adiponectin-activated signaling pathway; lipid transport; and positive regulation of protein serine/threonine kinase activity. Located in basal plasma membrane and endoplasmic reticulum. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; phalanx; and sensory organ. Orthologous to human SLC27A1 (solute carrier family 27 member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slc27a1 Products(8)

mRNA Protein Name
NM_001357180.1 NP_001344109.1 long-chain fatty acid transport protein 1
NM_001357181.1 NP_001344110.1 long-chain fatty acid transport protein 1
NM_001357182.1 NP_001344111.1 long-chain fatty acid transport protein 1
NM_011977.4 NP_036107.1 long-chain fatty acid transport protein 1
NM_001357180.1 NP_001344109.1 long-chain fatty acid transport protein 1
NM_001357181.1 NP_001344110.1 long-chain fatty acid transport protein 1
NM_001357182.1 NP_001344111.1 long-chain fatty acid transport protein 1
NM_011977.4 NP_036107.1 long-chain fatty acid transport protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables fatty acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
7954810 MGI
enables fatty acid transmembrane transporter activity IGI
IGI: Inferred from genetic interaction
18258213 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
12566451 MGI
enables long-chain fatty acid-CoA ligase activity IDA
IDA: Inferred from direct assay
12235169 MGI
enables oleoyl-CoA ligase activity IMP
IMP: Inferred from mutant phenotype
23024797 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
28178239 MGI
enables protein serine/threonine kinase activator activity IGI
IGI: Inferred from genetic interaction
20667975 MGI
enables protein serine/threonine kinase activator activity IMP
IMP: Inferred from mutant phenotype
19560442 MGI
enables very long-chain fatty acid-CoA ligase activity IDA
IDA: Inferred from direct assay
18258213 MGI
enables very long-chain fatty acid-CoA ligase activity IMP
IMP: Inferred from mutant phenotype
10593920 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within adiponectin-activated signaling pathway IMP
IMP: Inferred from mutant phenotype
20667975 MGI
acts upstream of or within fatty acid transport IDA
IDA: Inferred from direct assay
9671728 MGI
acts upstream of or within fatty acid transport IMP
IMP: Inferred from mutant phenotype
17130465 MGI
involved in glucose import in response to insulin stimulus IMP
IMP: Inferred from mutant phenotype
23024797 MGI
involved in long-chain fatty acid import into cell IDA
IDA: Inferred from direct assay
7954810 MGI
involved in long-chain fatty acid import into cell IMP
IMP: Inferred from mutant phenotype
23024797 MGI
acts upstream of or within long-chain fatty acid transport IMP
IMP: Inferred from mutant phenotype
16611988 MGI
acts upstream of or within medium-chain fatty acid transport IGI
IGI: Inferred from genetic interaction
18258213 MGI
acts upstream of or within positive regulation of heat generation IMP
IMP: Inferred from mutant phenotype
17130465 MGI
involved in positive regulation of triglyceride biosynthetic process IDA
IDA: Inferred from direct assay
12235169 MGI
acts upstream of or within response to cold IMP
IMP: Inferred from mutant phenotype
17130465 MGI
acts upstream of or within response to insulin IMP
IMP: Inferred from mutant phenotype
14991074 MGI
Cellular Component GO Annotation Evidence Reference Source
located in basal plasma membrane IDA
IDA: Inferred from direct assay
28035674 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
15496455 MGI
located in endoplasmic reticulum IMP
IMP: Inferred from mutant phenotype
23024797 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
7954810 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

long-chain fatty acid transport protein 1

arachidonate--CoA ligase

fatty acid transport protein 1

long-chain-fatty-acid--CoA ligase

very long-chain acyl-CoA synthetase

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16240 Slc27a1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13144 SLC27A1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc27a1 NCBI NCBI:376497