2. Gene
  3. SRPK3 - SRSF protein kinase 3 Gene

SRPK3 - SRSF protein kinase 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MSSK1; STK23; MSSK-1

Gene ID: 26576 | Gene type: protein coding

About SRPK3

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:153,781,041-153,785,730 (from NCBI)

This gene has 8 transcripts (splice variants), 262 orthologues and 19 paralogues. Biased expression in heart (RPKM 9.9), prostate (RPKM 3.3) and 7 other tissues.

Summary

This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

SRPK3 Products(3)

mRNA Protein Name
NM_001170760.2 NP_001164231.1 SRSF protein kinase 3 isoform 2
NM_001170761.2 NP_001164232.1 SRSF protein kinase 3 isoform 3
NM_014370.4 NP_055185.2 SRSF protein kinase 3 isoform 1

SRPK3 Protein Structure

Pkinase

Pkinase: Protein kinase domain (79 - 221)

Pkinase

Pkinase: Protein kinase domain (402 - 565)

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  • 567 a.a.
Protein Preferred Names Protein Names

SRSF protein kinase 3

SFRS protein kinase 3

Recombinant SRPK3 Proteins

Cat. No. Product Name Accession Purity
HY-P76659 SRPK3 Protein, Human (sf9, GST) Q9UPE1-4/NP_001164231.1 (M1-P566) ≥95%

Related Diseases

Diseases Alias
Tonne-Kalscheuer Syndrome

TOKAS

Mrx61

Intellectual Developmental Disorder With Or Without Hand And Foot Anomalies, Genital Anomalies, Or Congenital Diaphragmatic Hernia

Mental Retardation, X-Linked 61

X-Linked Mental Retardation 61
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148518 MSC-1186 Inhibitor 99.42% Unkown
HY-113831 CLK1/2-IN-3 Inhibitor / Unkown
HY-RS13779 SRPK3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SRPK3 RGD RGD:727856
Macaca mulatta SRPK3 VGNC VGNC:77914
Bos taurus SRPK3 VGNC VGNC:35290
Mus musculus SRPK3 MGD MGI:1891338
Canis familiaris SRPK3 VGNC VGNC:46812
Others SRPK3 NCBI