2. Gene
  3. Ppia - peptidylprolyl isomerase A Gene

Ppia - peptidylprolyl isomerase A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cphn; CypA; SP18; CyP-18

Gene ID: 268373 | Gene type: protein coding

About Ppia

Summary

Enables Integrin binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in platelet aggregation. Acts upstream of or within neuron differentiation. Located in extracellular space and myelin sheath. Is expressed in several structures, including early conceptus; gonad; hemolymphoid system gland; liver; and skeletal muscle. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to human PPIA (peptidylprolyl isomerase A). [provided by Alliance of Genome Resources, Apr 2022]

Ppia Products(1)

mRNA Protein Name
NM_008907.2 NP_032933.1 peptidyl-prolyl cis-trans isomerase A
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables integrin binding IDA
IDA: Inferred from direct assay
24429998 MGI
enables peptidyl-prolyl cis-trans isomerase activity IMP
IMP: Inferred from mutant phenotype
24429998 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16352598 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within neuron differentiation IMP
IMP: Inferred from mutant phenotype
16352598 MGI
involved in platelet activation IMP
IMP: Inferred from mutant phenotype
24429998 MGI
involved in platelet aggregation IMP
IMP: Inferred from mutant phenotype
24429998 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
29921611 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peptidyl-prolyl cis-trans isomerase A

PPIase A

cyclophilin A

cyclosporin A-binding protein

rotamase A

Recombinant Ppia Proteins

Cat. No. Product Name Accession Purity
HY-P70007 Cyclophilin A Protein, Mouse (solution) P17742 (M1-L164) ≥95%
HY-P74212 Cyclophilin A Protein, Mouse (His) P17742/NP_032933.1 (M1-L164) ≥95%
HY-P70007A Cyclophilin A Protein, Mouse P17742 (M1-L164) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10946 PPIA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppia NCBI NCBI:5478