CADPS - Cadps calcium dependent secretion activator Gene

Rattus norvegicus

Also known as Caps; Caps1; Caps2

Gene ID: 26989 | Gene type: protein coding

About CADPS

Summary

Enables calcium ion binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in positive regulation of calcium ion-dependent exocytosis. Located in dense core granule. Is active in glutamatergic synapse and presynapse. Is extrinsic component of neuronal dense core vesicle membrane. Orthologous to human CADPS (calcium dependent secretion activator). [provided by Alliance of Genome Resources, Apr 2022]

CADPS Products(1)

mRNA	Protein	Name
NM_013219.2	NP_037351.2	calcium-dependent secretion activator 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables calcium ion binding	IDA IDA: Inferred from direct assay	9289490	RGD
enables phosphatidylinositol-4,5-bisphosphate binding	IDA IDA: Inferred from direct assay	9525942	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	19805029	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of calcium ion-dependent exocytosis	IMP IMP: Inferred from mutant phenotype	9289490	RGD
involved in positive regulation of exocytosis	IMP IMP: Inferred from mutant phenotype	24356451	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in dense core granule	IDA IDA: Inferred from direct assay	24356451	RGD
is active in extrinsic component of neuronal dense core vesicle membrane	IDA IDA: Inferred from direct assay	9697858	RGD
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	14530279	RGD
is active in presynapse	IDA IDA: Inferred from direct assay	14530279	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

calcium-dependent secretion activator 1

CAPS-1	Ca++-dependent secretion activator
Ca2+ dependent secretion activator	Ca2+-dependent activator protein
Ca<2+-dependent activator protein for secretion	calcium-dependent activator protein for secretion 1
calcium-dependent secretion activator 1

CADPS Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Cadps	Q62717	Stx1a	Rattus norvegicus	P32851	Density Sedimentation	19805029

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01823	CADPS Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS01824	CADPS2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	CADPS	NCBI	NCBI:8618

Name
Email *

	Sorry, but the email address you supplied was invalid.