ZBTB11 - zinc finger and BTB domain containing 11 Gene

Homo sapiens

Also known as MRT69; ZNF913; ZNF-U69274

Gene ID: 27107 | Gene type: protein coding

About ZBTB11

Cytogenetic location: 3q12.3 Genomic coordinates (GRCh38): 3:101,648,889-101,677,132 (from NCBI)

This gene has 15 transcripts (splice variants), 213 orthologues, 38 paralogues and is associated with 1 phenotype. Ubiquitous expression in bone marrow (RPKM 8.1), testis (RPKM 5.9) and 25 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Located in nucleoplasm. Implicated in autosomal recessive non-syndromic intellectual disability. [provided by Alliance of Genome Resources, Apr 2022]

ZBTB11 Products(1)

mRNA	Protein	Name
NM_014415.4	NP_055230.2	zinc finger and BTB domain-containing protein 11

ZBTB11 Protein Structure

BTB

zf-C2H2

zf-C2H2_4

zf-H2C2_2

zf-C2H2

zf-H2C2_2

0
200
400
600
800
1000
1053 a.a.

Protein Preferred Names

Protein Names

zinc finger and BTB domain-containing protein 11

Related Diseases

Diseases

Alias

Intellectual Developmental Disorder, Autosomal Recessive 69

MRT69	Mental Retardation, Autosomal Recessive 69
Autosomal Recessive Intellectual Developmental Disorder 69

Chromosome 3q13.31 Deletion Syndrome

3q13 Microdeletion Syndrome	Monosomy 3q13
Chromosome 3, Monosomy 3q13	Del(3)(Q13)

Syndromic Intellectual Disability

Galactosemia Iii

Galactose Epimerase Deficiency	Gale Deficiency
Udp-Galactose-4-Epimerase Deficiency	Epimerase Deficiency Galactosemia
Galactosemia Type 3	Gale-D
Uridine Diphosphate Galactose-4-Epimerase Deficiency	GALAC3
Galactosemia 3	Generalized Uridine Diphosphate Galactose-4-Epimerase Deficiency
Erythrocyte Uridine Diphosphate Galactose-4-Epimerase Deficiency	Galactosemia Type Iii
Udp-Galactose-4'-Epimerase Deficiency	Generalized Galactose Epimerase Deficiency
Generalized Gale Deficiency	Generalized Gale-D
Generalized Udp-Galactose-4-Epimerase Deficiency	Generalized Epimerase Deficiency Galactosemia
Erythrocyte Galactose Epimerase Deficiency	Erythrocyte Gale Deficiency
Erythrocyte Gale-D	Erythrocyte Udp-Galactose-4-Epimerase Deficiency
Erythrocyte Epimerase Deficiency Galactosemia	Galactosemias
Classical Galactosemia	Udpglucose 4-Epimerase Deficiency Disease

Combined Malonic And Methylmalonic Aciduria

CMAMMA	Combined Malonic And Methylmalonic Acidemia
Aciduria, Combined Malonic And Methylmalonic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-161767	JWJ-01-306		/	Unkown
HY-RS15961	ZBTB11 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ZBTB11	RGD	RGD:1308275
Mus musculus	ZBTB11	MGD	MGI:2443876
Felis catus	ZBTB11	VGNC	VGNC:102871
Bos taurus	ZBTB11	VGNC	VGNC:37059
Macaca mulatta	ZBTB11	VGNC	VGNC:82563
Canis familiaris	ZBTB11	VGNC	VGNC:48521

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