HCAR1 - hydroxycarboxylic acid receptor 1 Gene

Homo sapiens

Also known as HCA1; GPR81; LACR1; FKSG80; GPR104; TAGPCR; TA-GPCR

Gene ID: 27198 | Gene type: protein coding

About HCAR1

Cytogenetic location: 12q24.31 Genomic coordinates (GRCh38): 12:122,726,076-122,730,844 (from NCBI)

This gene has 1 transcript (splice variant), 172 orthologues and 15 paralogues.

Summary

G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM, Feb 2005]

HCAR1 Products(1)

mRNA	Protein	Name
NM_032554.4	NP_115943.1	hydroxycarboxylic acid receptor 1

HCAR1 Protein Structure

7tm_1

0
100
200
300
346 a.a.

Protein Preferred Names

Protein Names

hydroxycarboxylic acid receptor 1

G protein-coupled receptor 104

Related Diseases

Diseases

Alias

Pellagra

Niacin Deficiency	Niacin-Tryptophan Deficiency
Pellagroid Syndrome

Diversion Colitis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B2227	Lactate		91.61%	Unkown

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06037	HCAR1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	HCAR1	MGD	MGI:2441671
Canis familiaris	HCAR1	VGNC	VGNC:41613
Bos taurus	HCAR1	VGNC	VGNC:29769
Rattus norvegicus	HCAR1	RGD	RGD:1586364

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