2. Gene
  3. GMFB - glia maturation factor beta Gene

GMFB - glia maturation factor beta Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GMF

Gene ID: 2764 | Gene type: protein coding

About GMFB

Cytogenetic location: 14q22.2 Genomic coordinates (GRCh38): 14:54,474,485-54,488,980 (from NCBI)

This gene has 10 transcripts (splice variants), 204 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 45.0), colon (RPKM 21.0) and 24 other tissues.

Summary

Predicted to enable Arp2/3 complex binding activity. Predicted to be involved in actin filament debranching and negative regulation of Arp2/3 complex-mediated actin nucleation. Predicted to act upstream of or within learning and locomotory behavior. [provided by Alliance of Genome Resources, Apr 2022]

GMFB Products(1)

mRNA Protein Name
NM_004124.3 NP_004115.1 glia maturation factor beta

GMFB Protein Structure

Cofilin_ADF

Cofilin_ADF: Cofilin/tropomyosin-type actin-binding protein (13 - 138)

  • 0
  • 100
  • 142 a.a.
Protein Preferred Names Protein Names

glia maturation factor beta

GMF-beta

Recombinant GMFB Proteins

Cat. No. Product Name Accession Purity
HY-P7362 Glia maturation factor beta/GMFB Protein, Human P60983 (M1-H142) ≥95%
HY-P70387 Glia maturation factor beta/GMFB Protein, Human (His) P60983 (M1-H142) ≥95%

Related Diseases

Diseases Alias
Arthrogryposis Multiplex Congenita 2, Neurogenic Type

Arthrogryposis Multiplex Congenita, Neurogenic Type

Amcn

Arthrogryposis Multiplex Congenita Neurogenic Type

AMC2

Amc, Neurogenic Type

Neurogenic-Type Arthrogryposis Multiplex Congenita-2

Amc Neurogenic Type

Neurogenic Type Of Amc

Neurogenic Arthrogryposis Multiplex Congenita

Arthrogryposis Multiplex Congenita, Neurogenic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05518 GMFB Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus GMFB VGNC VGNC:80964
Macaca mulatta GMFB VGNC VGNC:108300
Canis familiaris GMFB VGNC VGNC:41288
Rattus norvegicus GMFB RGD RGD:70910
Bos taurus GMFB VGNC VGNC:29434
Mus musculus GMFB MGD MGI:1927133
Others GMFB NCBI