SSX7 - SSX family member 7 Gene

Homo sapiens

Gene ID: 280658 | Gene type: protein coding

About SSX7

Cytogenetic location: Xp11.22 Genomic coordinates (GRCh38): X:52,644,061-52,654,900 (from NCBI)

This gene has 1 transcript (splice variant), 104 orthologues and 7 paralogues. Low expression observed in reference dataset.

Summary

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in Cancer patients, and are potentially useful targets in Cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. [provided by RefSeq, Jul 2008]

SSX7 Products(1)

mRNA	Protein	Name
NM_173358.2	NP_775494.1	protein SSX7

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SSX7 Protein Structure

SSXRD

0
100
188 a.a.

Protein Preferred Names

Protein Names

protein SSX7

synovial sarcoma, X breakpoint 7

SSX7 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SSX7	Q7RTT5	LRRC45	Homo sapiens	Q96CN5	Validated Y2H	32296183
Intra	SSX7	Q7RTT5	LRRC45	Homo sapiens	Q96CN5	Y2H Prey Pooling	32296183
Intra	SSX7	Q7RTT5	CIB1	Homo sapiens	Q99828	Validated Y2H	32296183
Intra	SSX7	Q7RTT5	CIB1	Homo sapiens	Q99828	Y2H Array	32296183
Intra	SSX7	Q7RTT5	CIB1	Homo sapiens	Q99828	Y2H Prey Pooling	32296183
Intra	SSX7	Q7RTT5	SERTAD1	Homo sapiens	Q9UHV2	Y2H Prey Pooling	32296183
Intra	SSX7	Q7RTT5	SERTAD1	Homo sapiens	Q9UHV2	Validated Y2H	32296183
Intra	SSX7	Q7RTT5	DNAAF11	Homo sapiens	Q86X45	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13842	SSX7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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