LGALS9B - galectin 9B Gene

Homo sapiens

Gene ID: 284194 | Gene type: protein coding

About LGALS9B

This gene has 6 transcripts (splice variants), 350 orthologues and 16 paralogues. Biased expression in stomach (RPKM 25.2), gall bladder (RPKM 10.0) and 4 other tissues.

Summary

This gene was initially thought to represent a pseudogene of Galectin 9; however, this transcript has good exon-intron structure and encodes a predicted protein of the same size as and highly similar to Galectin 9. This gene is one of two similar loci on chromosome 17p similar to Galectin 9 and now thought to be protein-encoding. This gene is the more centromeric gene. [provided by RefSeq, Jul 2008]

LGALS9B Products(2)

mRNA	Protein	Name
NM_001042685.3	NP_001036150.1	galectin-9B isoform 2
NM_001367292.2	NP_001354221.1	galectin-9B isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LGALS9B Protein Structure

Gal-bind_lectin

0
100
200
300
356 a.a.

Protein Preferred Names

Protein Names

galectin-9B

gal-9B

LGALS9B Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	LGALS9B	Q3B8N2	ABI2	Homo sapiens	Q9NYB9-2	Y2H Prey Pooling	32296183
Intra	LGALS9B	Q3B8N2	ABI2	Homo sapiens	Q9NYB9-2	Validated Y2H	32296183
Intra	LGALS9B	Q3B8N2	ABI2	Homo sapiens	Q9NYB9-2	Y2H Array	32296183
Intra	LGALS9B	Q3B8N2	ATPAF2	Homo sapiens	Q8N5M1	Validated Y2H	32296183
Intra	LGALS9B	Q3B8N2	NTAQ1	Homo sapiens	Q96HA8	Validated Y2H	32296183
Intra	LGALS9B	Q3B8N2	WWP2	Homo sapiens	O00308	Y2H Array	29892012
Intra	LGALS9B	Q3B8N2	WWP2	Homo sapiens	O00308	Y2H Array	31515488
Intra	LGALS9B	Q3B8N2	WWP2	Homo sapiens	O00308	Validated Y2H	25416956
Intra	LGALS9B	Q3B8N2	DAB1	Homo sapiens	O75553	Y2H Array	25416956
Intra	LGALS9B	Q3B8N2	DAB1	Homo sapiens	O75553	Y2H Prey Pooling	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07611	LGALS9B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	LGALS9B	MGD	MGI:109496

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