2. Gene
  3. METRNL - meteorin like, glial cell differentiation regulator Gene

METRNL - meteorin like, glial cell differentiation regulator Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 284207 | Gene type: protein coding

About METRNL

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:83,079,609-83,095,122 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 254 orthologues and 1 paralogue. Ubiquitous expression in colon (RPKM 12.0), kidney (RPKM 11.4) and 25 other tissues.

Summary

Predicted to enable hormone activity. Predicted to be involved in several processes, including brown fat cell differentiation; energy homeostasis; and positive regulation of brown fat cell differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

METRNL Products(2)

mRNA Protein Name
NM_001004431.3 NP_001004431.1 meteorin-like protein isoform 1 precursor
NM_001363853.2 NP_001350782.1 meteorin-like protein isoform 2
Protein Preferred Names Protein Names

meteorin-like protein

cometin

Recombinant METRNL Proteins

Cat. No. Product Name Accession Purity
HY-P71569 METRNL/Meteorin-like Protein, Human (His-SUMO) Q641Q3-1 (Q46-D311) ≥95%

Related Diseases

Diseases Alias
Bardet-Biedl Syndrome 12

BBS12

Bardet-Biedl Syndrome

Bbs

Bardet-Biedl Syndrome, Type 12
Bladder Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Bladder

Epidermoid Carcinoma Of The Urinary Bladder

Carcinoma Squamous Cell Bladder
Primary Cutaneous Amyloidosis

Plca

Primary Localized Cutaneous Amyloidosis

Familial Primary Localized Cutaneous Amyloidosis

Amyloidosis Ix

Lichen Amyloidosis Familial

Amyloidosis, Primary Cutaneous

Pca

Amyloidosis 9

Amyloidosis Familial Cutaneous Lichen

Fplca

Familial Lichen Amyloidosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08352 METRNL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus METRNL RGD RGD:1359271
Felis catus METRNL VGNC VGNC:63457
Macaca mulatta METRNL VGNC VGNC:82184
Mus musculus METRNL MGD MGI:2384806
Bos taurus METRNL VGNC VGNC:31399
Others METRNL NCBI