Npc2 - NPC intracellular cholesterol transporter 2 Gene

Rattus norvegicus

Also known as re1

Gene ID: 286898 | Gene type: protein coding

About Npc2

Summary

Predicted to enable Cholesterol binding activity; Cholesterol transfer activity; and Enzyme binding activity. Predicted to be involved in Cholesterol homeostasis; Cholesterol transport; and response to virus. Predicted to be located in extracellular space and lysosome. Human ortholog(s) of this gene implicated in Niemann-Pick disease and Niemann-Pick disease type C2. Orthologous to human NPC2 (NPC intracellular Cholesterol transporter 2). [provided by Alliance of Genome Resources, Apr 2022]

Npc2 Products(1)

mRNA	Protein	Name
NM_173118.2	NP_775141.2	NPC intracellular cholesterol transporter 2 precursor

Protein Preferred Names

Protein Names

NPC intracellular cholesterol transporter 2

Niemann Pick type C2	Niemann-Pick disease, type C2
epididymal secretory protein 1	epididymal secretory protein E1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-111355B	Cholesteryl sulfate sodium		≥98.0%	Unkown
HY-RS09476	NPC2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-W014780	α-Amylcinnamaldehyde		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Npc2	NCBI	NCBI:10577
Mus musculus	Npc2	NCBI	NCBI:67963

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