Mc3r - melanocortin 3 receptor Gene

Rattus norvegicus

Gene ID: 29310 | Gene type: protein coding

About Mc3r

Primary_assembly 3: 161,016,347-161,017,444 forward strand.mRatBN7.2:CM026976.1

This gene has 1 transcript (splice variant), 141 orthologues, 18 paralogues and is associated with 2 phenotypes.

Summary

Enables Melanocortin Receptor activity and peptide hormone binding activity. Involved in several processes, including adenylate cyclase-modulating G protein-coupled receptor signaling pathway; homoiothermy; and sodium ion homeostasis. Predicted to be integral component of plasma membrane. Predicted to be active in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in obesity. Orthologous to human MC3R (melanocortin 3 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Mc3r Products(1)

mRNA	Protein	Name
NM_001025270.4	NP_001020441.3	melanocortin receptor 3

Mc3r Protein Structure

7tmA_MC3R

0
100
200
300
323 a.a.

Protein Preferred Names

Protein Names

melanocortin receptor 3

MC3-R

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-147301	Resomelagon	Agonist	99.63%	Phase 2

Pre-clinical Phase

Bioactive Molecules (10)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P0227	SHU 9119		99.95%	Unkown
HY-P0097A	Nonapeptide-1 acetate salt	Antagonist	98.70%	Unkown
HY-P1217	[D-Trp8]-γ-MSH	Agonist	99.57%	Unkown
HY-P1214	γ1-MSH	Agonist	99.71%	Unkown
HY-P1531	γ-1-Melanocyte Stimulating Hormone (MSH), amide	Agonist	99.32%	Unkown
HY-P1209A	PG106 TFA	Antagonist	99.61%	Unkown
HY-P1217A	[D-Trp8]-γ-MSH TFA	Agonist	/	Unkown
HY-P1214A	γ1-MSH TFA	Agonist	/	Unkown
HY-P0097	Nonapeptide-1	Antagonist	99.04%	Unkown
HY-P0252B	α-MSH free acid	Agonist	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mc3r	NCBI	NCBI:4159

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