Mknk2 - MAPK interacting serine/threonine kinase 2 Gene

Rattus norvegicus

Gene ID: 299618 | Gene type: protein coding

About Mknk2

Primary_assembly 7: 9,039,728-9,050,827 forward strand.mRatBN7.2:CM026980.1

This gene has 2 transcripts (splice variants), 224 orthologues, 6 paralogues and is associated with 1 phenotype. Biased expression in Muscle (RPKM 36.3), Spleen (RPKM 34.2) and 9 other tissues.

Summary

Predicted to enable ATP binding activity; Calmodulin binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to arsenic-containing substance; intracellular signal transduction; and protein phosphorylation. Predicted to act upstream of or within extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in nuclear body. Predicted to be active in cytoplasm and nucleus. Orthologous to human MKNK2 (MAPK interacting serine/threonine kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Mknk2 Products(1)

mRNA	Protein	Name
NM_001011985.2	NP_001011985.1	MAP kinase-interacting serine/threonine-protein kinase 2

Mknk2 Protein Structure

PKc_like

0
100
200
300
400
459 a.a.

Protein Preferred Names

Protein Names

MAP kinase-interacting serine/threonine-protein kinase 2

MAP kinase signal-integrating kinase 2	MAP kinase-interacting serine/threonine kinase 2
MAPK signal-integrating kinase 2	mnk2

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-136848	SM1-71	Inhibitor	96.09%	Unkown
HY-148062	RSS0680		98.03%	Unkown
HY-RS08476	MKNK2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS08477	Mknk2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS08478	Mknk2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mknk2	NCBI	NCBI:2872

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