BICRA - BRD4 interacting chromatin remodeling complex associated protein Gene

Homo sapiens

Also known as CSS12; GLTSCR1; SMARCK1

Gene ID: 29998 | Gene type: protein coding

About BICRA

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:47,608,196-47,703,277 (from NCBI)

This gene has 4 transcripts (splice variants), 183 orthologues, 1 paralogue and is associated with 2 phenotypes. Ubiquitous expression in spleen (RPKM 1.9), prostate (RPKM 1.7) and 25 other tissues.

Summary

Enables transcription regulator activator activity. Involved in positive regulation of transcription, DNA-templated. Located in nucleus. Part of SWI/SNF complex. Implicated in Coffin-Siris syndrome. [provided by Alliance of Genome Resources, Apr 2022]

BICRA Products(2)

mRNA	Protein	Name
NM_001394372.1	NP_001381301.1	BRD4-interacting chromatin-remodeling complex-associated protein
NM_015711.3	NP_056526.3	BRD4-interacting chromatin-remodeling complex-associated protein

BICRA Protein Structure

GLTSCR1

0
300
600
900
1200
1560 a.a.

Protein Preferred Names

Protein Names

BRD4-interacting chromatin-remodeling complex-associated protein

BRD4 interacting chromatin remodelling complex associated protein

Related Diseases

Diseases

Alias

Coffin-Siris Syndrome 12

CSS12

Neuroma

Coffin-Siris Syndrome 1

Coffin-Siris Syndrome	Fifth Digit Syndrome
Css	CSS1
Mrd12	Mental Retardation, Autosomal Dominant 12
Hhid	Dwarfism-Onychodysplasia
Hypertrichosis, Hyperkeratosis, Mental Retardation, And Distinctive Facial Features	Autosomal Dominant Mental Retardation 12
Short Stature-Onychodysplasia.	Intellectual Disability With Absent Fifth Fingernail And Terminal Phalanx
Mental Retardation With Hypoplastic Fifth Fingernails And Toenails	Short Stature-Onychodysplasia
Coffin-Siris Syndrome, Type 1	Mental Retardation, Autosomal Dominant, Type 12

Hypertrichosis

Clark-Baraitser Syndrome

CLABARS	Baraitser Syndrome
Autosomal Dominant Intellectual Disability 49	Mental Retardation, Autosomal Dominant 49, Formerly
Mrd49, Formerly	Intellectual Developmental Disorder, Autosomal Dominant 49
Autosomal Dominant Mental Retardation 49	Intellectual Disability, Tall Stature, Obesity, Macrocephaly And Typical Facial Features
Mrd49	Progeria Short Stature Pigmented Nevi

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01500	BICRA Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	BICRA	VGNC	VGNC:38454
Felis catus	BICRA	VGNC	VGNC:82434
Mus musculus	BICRA	MGD	MGI:2154263
Bos taurus	BICRA	VGNC	VGNC:26494
Macaca mulatta	BICRA	VGNC	VGNC:70466
Rattus norvegicus	BICRA	RGD	RGD:1306385

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