2. Gene
  3. Ulk2 - unc-51 like autophagy activating kinase 2 Gene

Ulk2 - unc-51 like autophagy activating kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 303206 | Gene type: protein coding

About Ulk2

Primary_assembly 10: 46,454,030-46,530,407 reverse strand.mRatBN7.2:CM026983.1

This gene has 3 transcripts (splice variants), 206 orthologues, 2 paralogues and is associated with 4 phenotypes. Biased expression in Muscle (RPKM 159.8), Lung (RPKM 151.5) and 9 other tissues.

Summary

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including Autophagy of nucleus; macroautophagy; and protein phosphorylation. Predicted to be active in phagophore assembly site membrane. Orthologous to human ULK2 (unc-51 like Autophagy activating kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ulk2 Products(1)

mRNA Protein Name
NM_001191645.2 NP_001178574.1 serine/threonine-protein kinase ULK2

Ulk2 Protein Structure

STKc_ULK2

STKc_ULK2: cd14201 (1 - 271)

DUF3543

DUF3543: cl13493 (842 - 1051)

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  • 1059 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase ULK2

Unc-51 like kinase 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16966 SBI-0206965 Inhibitor 99.39% Unkown
HY-13018 MRT67307 Inhibitor 99.34% Unkown
HY-114490 ULK-101 Inhibitor 99.96% Unkown
HY-160699 DCC-3116 Inhibitor 99.25% Unkown
HY-137742 SBP-7455 Inhibitor 98.24% Unkown
HY-13018A MRT67307 hydrochloride Inhibitor / Unkown
HY-162100 MR-2088 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ulk2 NCBI NCBI:9706