2. Gene
  3. Cd34 - CD34 molecule Gene

Cd34 - CD34 molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 305081 | Gene type: protein coding

About Cd34

Summary

Predicted to enable carbohydrate binding activity and sulfate binding activity. Involved in glomerular filtration and mesangial cell-matrix adhesion. Located in apical plasma membrane; basal plasma membrane; and lysosome. Part of glomerular endothelium fenestra. Biomarker of diabetic retinopathy. Orthologous to human CD34 (CD34 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd34 Products(2)

mRNA Protein Name
NM_001107202.3 NP_001100672.1 hematopoietic progenitor cell antigen CD34 isoform 1 precursor
NM_001412747.1 NP_001399676.1 hematopoietic progenitor cell antigen CD34 isoform 2 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in glomerular filtration IEP
IEP: Inferred from expression pattern
18319274 RGD
involved in mesangial cell-matrix adhesion IEP
IEP: Inferred from expression pattern
18319274 RGD
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
18319274 RGD
located in basal plasma membrane IDA
IDA: Inferred from direct assay
18319274 RGD
part of glomerular endothelium fenestra IDA
IDA: Inferred from direct assay
18319274 RGD
located in lysosome IDA
IDA: Inferred from direct assay
18319274 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
18319274 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hematopoietic progenitor cell antigen CD34

CD34 antigen

Recombinant Cd34 Proteins

Cat. No. Product Name Accession Purity
HY-P74304 CD34 Protein, Rat (HEK293, Fc) B1PLB1 (E37-T291) ≥95%

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15306 Eltrombopag 99.94% Yes
HY-15306A Eltrombopag Olamine 99.96% Yes
Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-110208 BRD9876 98.82% Unkown
HY-106784 Ajoene ≥99.0% Unkown
HY-108417 Debio 0617B Inhibitor / Unkown
HY-125090 PHA-680626 / Unkown
HY-15001A Stemregenin 1 hydrochloride Antagonist / Unkown
HY-150239 BAY-364 Inhibitor / Unkown
HY-RS02236 CD34 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-150109A Purinostat Inhibitor / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990351 Anti-CD34 Antibody Inhibitor 99.90% Unkown
HY-P990274 Anti-Canine CD34 Antibody (1H6) / Unkown
HY-P990352 Anti-CD36 Antibody Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd34 NCBI NCBI:947
Canis familiaris Cd34 NCBI NCBI:415130
Macaca fascicularis Cd34 NCBI NCBI:101866926
Mus musculus Cd34 NCBI NCBI:12490
Macaca mulatta Cd34 NCBI NCBI:713858