2. Gene
  3. Cobl - cordon-bleu WH2 repeat protein Gene

Cobl - cordon-bleu WH2 repeat protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 305497 | Gene type: protein coding

About Cobl

Summary

Predicted to enable actin monomer binding activity. Predicted to be involved in actin filament organization; collateral sprouting in absence of injury; and positive regulation of cell projection organization. Predicted to act upstream of or within several processes, including chordate embryonic development; liver development; and notochord development. Located in cell cortex and plasma membrane. Orthologous to human COBL (cordon-bleu WH2 repeat protein). [provided by Alliance of Genome Resources, Apr 2022]

Cobl Products(9)

mRNA Protein Name
NM_001401101.1 NP_001388030.1 protein cordon-bleu isoform 1
NM_001401102.1 NP_001388031.1 protein cordon-bleu isoform 2
NM_001401103.1 NP_001388032.1 protein cordon-bleu isoform 3
NM_001401104.1 NP_001388033.1 protein cordon-bleu isoform 4
NM_001401105.1 NP_001388034.1 protein cordon-bleu isoform 5
NM_001401106.1 NP_001388035.1 protein cordon-bleu isoform 6
NM_001401108.1 NP_001388037.1 protein cordon-bleu isoform 7
NM_001401109.1 NP_001388038.1 protein cordon-bleu isoform 8
NM_001401112.1 NP_001388041.1 protein cordon-bleu isoform 10
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21725280 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell cortex IDA
IDA: Inferred from direct assay
21725280 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
21725280 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein cordon-bleu

cordon-bleu homolog

Cobl Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Cobl D3ZUI5 Pacsin1 Rattus norvegicus Q9Z0W5
IF
21725280
Intra
Cobl D3ZUI5 Pacsin1 Rattus norvegicus Q9Z0W5
Anti Bait CoIP
26334624
Intra
Cobl D3ZUI5 Pacsin1 Rattus norvegicus Q9Z0W5
Anti Bait CoIP
21725280
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02947 COBL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cobl NCBI NCBI:23242