2. Gene
  3. F12 - coagulation factor XII Gene

F12 - coagulation factor XII Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as HAF

Gene ID: 306761 | Gene type: protein coding

About F12

Summary

Predicted to enable serine-type endopeptidase activity. Involved in blood coagulation. Located in extracellular space. Used to study hyperhomocysteinemia. Human ortholog(s) of this gene implicated in angioedema (multiple); cerebrovascular disease (multiple); factor XII deficiency; and myocardial infarction. Orthologous to human F12 (coagulation factor XII). [provided by Alliance of Genome Resources, Apr 2022]

F12 Products(1)

mRNA Protein Name
NM_001014006.1 NP_001014028.1 coagulation factor XII precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
2324612 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coagulation factor XII

factor XII

hageman factor

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-150287 Insulin-Transferrin-Selenium, 100X / Unkown
HY-130260 KRAS inhibitor-4 Inhibitor / Unkown
HY-RS03479 CYP4F12 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04627 F12 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W760183 EM12-SO2F / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990150 Anti-Mouse TSLP Antibody (28F12) 95.00% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens F12 NCBI NCBI:2161
Canis familiaris F12 NCBI NCBI:489090
Macaca fascicularis F12 NCBI NCBI:101925781
Mus musculus F12 NCBI NCBI:58992
Susscrofa domestica F12 NCBI