2. Gene
  3. F12 - coagulation factor XII (Hageman factor) Gene

F12 - coagulation factor XII (Hageman factor) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as HAF; FXII

Gene ID: 58992 | Gene type: protein coding

About F12

Summary

This gene encodes a glycoprotein coagulation factor that plays an important role in the intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that is autoactivated upon contact with negatively charged surfaces or misfolded protein aggregates. Mice lacking the encoded protein have a severe defect in forming stable fibrin clots. [provided by RefSeq, Apr 2015]

F12 Products(1)

mRNA Protein Name
NM_021489.3 NP_067464.2 coagulation factor XII preproprotein
Protein Preferred Names Protein Names

coagulation factor XII

factor XII

hageman factor

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-150287 Insulin-Transferrin-Selenium, 100X / Unkown
HY-130260 KRAS inhibitor-4 Inhibitor / Unkown
HY-RS03479 CYP4F12 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04627 F12 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W760183 EM12-SO2F / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990150 Anti-Mouse TSLP Antibody (28F12) 95.00% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens F12 NCBI NCBI:2161
Canis familiaris F12 NCBI NCBI:489090
Macaca fascicularis F12 NCBI NCBI:101925781
Susscrofa domestica F12 NCBI
Rattus norvegicus F12 NCBI NCBI:306761