HUNK - hormonally up-regulated Neu-associated kinase Gene

Homo sapiens

Gene ID: 30811 | Gene type: protein coding

About HUNK

Cytogenetic location: 21q22.11 Genomic coordinates (GRCh38): 21:31,873,020-32,004,064 (from NCBI)

This gene has 4 transcripts (splice variants), 158 orthologues and 17 paralogues. Broad expression in placenta (RPKM 1.4), colon (RPKM 1.2) and 20 other tissues.

Summary

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]

HUNK Products(1)

mRNA	Protein	Name
NM_014586.2	NP_055401.1	hormonally up-regulated neu tumor-associated kinase

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	20133759	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HUNK Protein Structure

Pkinase

0
200
400
600
714 a.a.

Protein Preferred Names

Protein Names

hormonally up-regulated neu tumor-associated kinase

B19

Related Diseases

Diseases

Alias

Recombinase Activating Gene 1 Deficiency

Immunodeficiency 39

IMD39

Immunodeficiency, Type 39

Combined Cellular And Humoral Immune Defects With Granulomas

Combined Immunodeficiency With Skin Granulomas	CCHIDG
Cid Due To Rag 1/2 Deficiency	Combined Immunodeficiency Due To Rag 1/2 Deficiency
Combined Immunodeficiency With Granulomatosis	CHIDG
Immune Defects, Combined Cellular And Humoral With Granulomas

Immunodeficiency 44

IMD44

Baylisascariasis

Infection By Baylisascaris

Immunodeficiency 31b

IMD31B	Immunodeficiency 31b, Mycobacterial And Viral Infections, Autosomal Recessive
Autosomal Recessive Stat1 Deficiency	Predisposition To Severe Viral Infection Due To Stat1 Deficiency
Susceptibility To Viral And Mycobacterial Infections Due To Stat1 Deficiency	Stat1 Deficiency, Autosomal Recessive
Autosomal Recessive Immunodeficiency 31b, Mycobacterial And Viral Infections	Stat1 Deficiency
Autosomal Recessive Susceptibility To Mycobacterial And Viral Infections	Mycobacterial And Viral Infections Due To Complete Stat1 Deficiency
Immunodeficiency, Type 31b, Mycobacterial And Viral Infections, Autosomal Recessive

Cataract 18

Cataract, Autosomal Recessive Congenital 2	Catc2
CTRCT18	Autosomal Recessive Congenital Cataract 2
Cataract 18, Autosomal Recessive	Cataract 18 Autosomal Recessive
Cataract, Type 18

Cataract 44

CTRCT44	Total Early-Onset Cataract
Cataract 44 And Hypotrichosis	Cataract And Hypotrichosis
Cataract, Type 44

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06491	HUNK Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	HUNK	RGD	RGD:1565091
Bos taurus	HUNK	VGNC	VGNC:49999
Felis catus	HUNK	VGNC	VGNC:62858
Canis familiaris	HUNK	VGNC	VGNC:53027
Mus musculus	HUNK	MGD	MGI:1347352
Macaca mulatta	HUNK	VGNC	VGNC:73386
Others	HUNK	NCBI

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