2. Gene
  3. EIF4E3 - eukaryotic translation initiation factor 4E family member 3 Gene

EIF4E3 - eukaryotic translation initiation factor 4E family member 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as eIF-4E3; eIF4E-3

Gene ID: 317649 | Gene type: protein coding

About EIF4E3

Cytogenetic location: 3p13 Genomic coordinates (GRCh38): 3:71,659,363-71,754,773 (from NCBI)

This gene has 10 transcripts (splice variants), 263 orthologues and 3 paralogues. Ubiquitous expression in fat (RPKM 11.9), brain (RPKM 7.2) and 25 other tissues.

Summary

EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).[supplied by OMIM, Mar 2008]

EIF4E3 Products(5)

mRNA Protein Name
NM_001134649.3 NP_001128121.1 eukaryotic translation initiation factor 4E type 3 isoform b
NM_001134650.1 NP_001128122.1 eukaryotic translation initiation factor 4E type 3 isoform b
NM_001134651.2 NP_001128123.1 eukaryotic translation initiation factor 4E type 3 isoform a
NM_001282886.2 NP_001269815.1 eukaryotic translation initiation factor 4E type 3 isoform b
NM_173359.5 NP_775495.1 eukaryotic translation initiation factor 4E type 3 isoform b

EIF4E3 Protein Structure

IF4E

IF4E: Eukaryotic initiation factor 4E (48 - 211)

  • 0
  • 100
  • 200
  • 224 a.a.
Protein Preferred Names Protein Names

eukaryotic translation initiation factor 4E type 3

Related Diseases

Diseases Alias
Thymus Lymphoma

Thymic Lymphoma
Eyelid Disease

Eyelid Diseases

Eyelid Disorders
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04276 EIF4E3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris EIF4E3 VGNC VGNC:40285
Rattus norvegicus EIF4E3 RGD RGD:1586185
Felis catus EIF4E3 VGNC VGNC:61792
Mus musculus EIF4E3 MGD MGI:1914142
Bos taurus EIF4E3 VGNC VGNC:28411