IFNA8 - interferon alpha 8 Gene

Homo sapiens

Also known as IFN-alphaB

Gene ID: 3445 | Gene type: protein coding

About IFNA8

Cytogenetic location: 9p21.3 Genomic coordinates (GRCh38): 9:21,409,117-21,410,185 (from NCBI)

This gene has 1 transcript (splice variant), 585 orthologues and 16 paralogues.

Summary

Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including B cell activation; lymphocyte activation involved in immune response; and positive regulation of peptidyl-serine phosphorylation of STAT protein. Predicted to act upstream of or within defense response to virus. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

IFNA8 Products(1)

mRNA	Protein	Name
NM_002170.4	NP_002161.2	interferon alpha-8 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IFNA8 Protein Structure

Interferon

0
100
189 a.a.

Protein Preferred Names

Protein Names

interferon alpha-8

IFN-alpha-8

Recombinant IFNA8 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P73860	IFN-alpha B/IFNA8 Protein, Human (HEK293, His)	P32881/NP_002161.2 (C24-E189)	≥95%
HY-P73861	IFN-alpha B/IFNA8 Protein, Human (HEK293)	P32881/NP_002161.2 (N-G&P, C24-E189)	≥95%

Related Diseases

Diseases

Alias

St. Louis Encephalitis

Saint Louis Encephalitis	Neuroinvasive St. Louis Encephalitis Virus Infection
Encephalitis, St. Louis	Neuroinvasive Saint Louis Encephalitis Virus Infection
St. Louis Encephalitis Virus Infection	St. Louis Encephalitis Virus Neuroinvasive Disease
St. Louis Viral Disease	Type C Lethargic Encephalitis
Encephalitis Type C

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06578	IFNA8 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca fascicularis	IFNA8	NCBI	NCBI:102140954
Others	IFNA8	NCBI

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