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  3. Interferon & Receptors
  4. IFN-alpha
  5. Interferon alpha-B
  6. IFN-alpha B/IFNA8 Protein, Human (HEK293)

IFN-alpha B/IFNA8 Protein, Human (HEK293)

Cat. No.: HY-P73861
SDS COA Handling Instructions

IFN-alpha B/IFNA8 Protein, synthesized by macrophages, displays potent antiviral activities. It stimulates the production of essential enzymes—a protein kinase and an oligoadenylate synthetase—that are pivotal in cellular defense against viral infections. IFN-alpha B/IFNA8 Protein, Human (HEK293) is the recombinant human-derived IFN-alpha B/IFNA8 protein, expressed by HEK293 , with tag free.

For research use only. We do not sell to patients.

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Size Price Stock Quantity
2 μg $65 In-stock
10 μg $175 In-stock
50 μg $480 In-stock
100 μg   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

IFN-alpha B/IFNA8 Protein, synthesized by macrophages, displays potent antiviral activities. It stimulates the production of essential enzymes—a protein kinase and an oligoadenylate synthetase—that are pivotal in cellular defense against viral infections. IFN-alpha B/IFNA8 Protein, Human (HEK293) is the recombinant human-derived IFN-alpha B/IFNA8 protein, expressed by HEK293 , with tag free.

Background

IFN-alpha B/IFNA8 Protein, produced by macrophages, exhibits potent antiviral activities. It stimulates the production of two crucial enzymes: a protein kinase and an oligoadenylate synthetase. These enzymes play crucial roles in the cellular defense against viral infections.

Biological Activity

Measured in antiviral assays using WISH cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is 0.2-2 pg/mL.

Species

Human

Source

HEK293

Tag

Tag Free

Accession

P32881/NP_002161.2 (N-G&P, C24-E189)

Gene ID
Molecular Construction
N-term
Gly-Pro
IFNA8 (C24-E189)
Accession # P32881/NP_002161.2
C-term
Synonyms
IFNA8; IFN-alpha 8; IFN-alpha B2; Interferon alpha-8; Interferon alpha-B
AA Sequence

CDLPQTHSLGNRRALILLAQMRRISPFSCLKDRHDFEFPQEEFDDKQFQKAQAISVLHEMIQQTFNLFSTKDSSAALDETLLDEFYIELDQQLNDLESCVMQEVGVIESPLMYEDSILAVRKYFQRITLYLTEKKYSSCAWEVVRAEIMRSFSLSINLQKRLKSKE

Molecular Weight

Approximately 26 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Appearance

Solution.

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

IFN-alpha B/IFNA8 Protein, Human (HEK293) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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IFN-alpha B/IFNA8 Protein, Human (HEK293)
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HY-P73861
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