2. Gene
  3. SLCO4C1 - solute carrier organic anion transporter family member 4C1 Gene

SLCO4C1 - solute carrier organic anion transporter family member 4C1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as OATPX; OATP-H; OATP-M1; OATP4C1; PRO2176; SLC21A20

Gene ID: 353189 | Gene type: protein coding

About SLCO4C1

Cytogenetic location: 5q21.1 Genomic coordinates (GRCh38): 5:102,233,986-102,296,284 (from NCBI)

This gene has 1 transcript (splice variant), 136 orthologues and 10 paralogues. Biased expression in kidney (RPKM 21.4), lung (RPKM 4.2) and 4 other tissues.

Summary

SLCO4C1 belongs to the organic anion transporter (OATP) family. OATPs are involved in the membrane transport of bile acids, conjugated Steroids, thyroid hormone, eicosanoids, Peptides, and numerous drugs in many tissues (Mikkaichi et al., 2004 [PubMed 14993604]).[supplied by OMIM, Mar 2008]

SLCO4C1 Products(1)

mRNA Protein Name
NM_180991.5 NP_851322.3 solute carrier organic anion transporter family member 4C1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables organic anion transmembrane transporter activity IDA
IDA: Inferred from direct assay
19129463 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLCO4C1 Protein Structure

OATP

OATP: Organic Anion Transporter Polypeptide (OATP) family (107 - 664)

Kazal_2

Kazal_2: Kazal-type serine protease inhibitor domain (507 - 547)

  • 0
  • 200
  • 400
  • 600
  • 724 a.a.
Protein Preferred Names Protein Names

solute carrier organic anion transporter family member 4C1

organic anion transporter M1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-128442 Phenyl sulfate 99.56% Unkown
HY-RS13359 SLCO4C1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLCO4C1 VGNC VGNC:34955
Mus musculus SLCO4C1 MGD MGI:2442784
Macaca mulatta SLCO4C1 VGNC VGNC:77764
Rattus norvegicus SLCO4C1 RGD RGD:1303048
Canis familiaris SLCO4C1 VGNC VGNC:46499
Felis catus SLCO4C1 VGNC VGNC:65448