CA13 - carbonic anhydrase 13 Gene

Homo sapiens

Also known as CAXIII

Gene ID: 377677 | Gene type: protein coding

About CA13

Cytogenetic location: 8q21.2 Genomic coordinates (GRCh38): 8:85,245,458-85,284,073 (from NCBI)

This gene has 5 transcripts (splice variants), 291 orthologues and 14 paralogues. Broad expression in small intestine (RPKM 7.8), duodenum (RPKM 6.3) and 18 other tissues.

Summary

Carbonic anhydrases (CAs) are a family of zinc metalloenzymes. For background information on the CA family, see MIM 114800.[supplied by OMIM, Mar 2008]

CA13 Products(1)

mRNA	Protein	Name
NM_198584.3	NP_940986.1	carbonic anhydrase 13

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CA13 Protein Structure

Carb_anhydrase

0
100
200
262 a.a.

Protein Preferred Names

Protein Names

carbonic anhydrase 13

CA-XIII

CA13 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CA13	Q8N1Q1	CRACR2B	Homo sapiens	Q8N4Y2-3	Y2H Prey Pooling	32296183
Intra	CA13	Q8N1Q1	CRACR2B	Homo sapiens	Q8N4Y2-3	Validated Y2H	32296183
Intra	CA13	Q8N1Q1	CRACR2B	Homo sapiens	Q8N4Y2-3	Y2H Array	32296183
Intra	CA13	Q8N1Q1	CRTC3	Homo sapiens	Q6UUV7	Y2H Prey Pooling	32296183
Intra	CA13	Q8N1Q1	CRTC3	Homo sapiens	Q6UUV7	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CA13 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7726	Carbonic Anhydrase 13 Protein, Human (His)	Q8N1Q1 (M1-F261)	≥95%

Related Diseases

Diseases

Alias

Intracranial Hypertension, Idiopathic

Pseudotumor Cerebri	Idiopathic Intracranial Hypertension
Benign Intracranial Hypertension	Iih
Benign Intracran. Hypt.

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01766	CA13 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CA13	VGNC	VGNC:60243
Macaca mulatta	CA13	VGNC	VGNC:83987
Mus musculus	CA13	MGD	MGI:1931322
Bos taurus	CA13	VGNC	VGNC:26651
Canis familiaris	CA13	VGNC	VGNC:38608
Rattus norvegicus	CA13	RGD	RGD:1560453
Others	CA13	NCBI

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