2. Gene
  3. KIF3C - kinesin family member 3C Gene

KIF3C - kinesin family member 3C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 3797 | Gene type: protein coding

About KIF3C

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:25,926,598-25,982,497 (from NCBI)

This gene has 7 transcripts (splice variants), 274 orthologues and 41 paralogues. Biased expression in brain (RPKM 57.3), adrenal (RPKM 4.3) and 1 other tissue.

Summary

Predicted to enable microtubule binding activity and microtubule motor activity. Predicted to be involved in microtubule-based movement. Predicted to act upstream of or within organelle transport along microtubule. Predicted to be located in microtubule cytoskeleton; neuronal cell body; and neuronal ribonucleoprotein granule. Predicted to be part of Kinesin complex. Predicted to be active in microtubule. [provided by Alliance of Genome Resources, Apr 2022]

KIF3C Products(1)

mRNA Protein Name
NM_002254.8 NP_002245.4 kinesin-like protein KIF3C
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17043677 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KIF3C Protein Structure

Kinesin

Kinesin: Kinesin motor domain (16 - 258)

Kinesin

Kinesin: Kinesin motor domain (282 - 365)

  • 0
  • 200
  • 400
  • 600
  • 793 a.a.
Protein Preferred Names Protein Names

kinesin-like protein KIF3C

KIF3C variant protein

KIF3C Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
KIF3C O14782 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra
KIF3C O14782 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra
KIF3C O14782 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra
KIF3C O14782 MCC Homo sapiens P23508
Validated Y2H
32296183
Intra
KIF3C O14782 MCC Homo sapiens P23508
Y2H Prey Pooling
32296183
Intra
KIF3C O14782 MCC Homo sapiens P23508
Y2H Array
32296183
Intra
KIF3C O14782 DISC1 Homo sapiens Q9NRI5
Y2H
17043677
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07287 KIF3C Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris KIF3C VGNC VGNC:42406
Felis catus KIF3C VGNC VGNC:67943
Bos taurus KIF3C VGNC VGNC:30604
Macaca mulatta KIF3C VGNC VGNC:74019
Rattus norvegicus KIF3C RGD RGD:621538
Mus musculus KIF3C MGD MGI:107979