KCTD4 - potassium channel tetramerization domain containing 4 Gene

Homo sapiens

Also known as bA321C24.3

Gene ID: 386618 | Gene type: protein coding

About KCTD4

This gene has 1 transcript (splice variant), 204 orthologues and 13 paralogues. Biased expression in brain (RPKM 6.1), skin (RPKM 1.4) and 1 other tissue.

Summary

Predicted to be involved in protein homooligomerization. [provided by Alliance of Genome Resources, Apr 2022]

KCTD4 Products(1)

mRNA	Protein	Name
NM_198404.3	NP_940686.2	BTB/POZ domain-containing protein KCTD4

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25910212	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KCTD4 Protein Structure

BTB_2

0
100
200
259 a.a.

Protein Preferred Names

Protein Names

BTB/POZ domain-containing protein KCTD4

potassium channel tetramerisation domain containing 4

Related Diseases

Diseases

Alias

Gastrointestinal Adenoma

Gi Adenoma

Digestive System Adenoma

Granulomatous Disease, Chronic, X-Linked

CGDX	Chronic Granulomatous Disease, X-Linked
X-Linked Chronic Granulomatous Disease	Cgd
Cytochrome B-Negative Granulomatous Disease, Chronic, X-Linked	Cdgx
X-Linked Chronic Cytochrome B-Negative Granulomatous Disease	Chronic Granulomatous Disease Cytochrome B-Negative X-Linked
Chronic Granulomatous Disease Cytochrome B-Positive X-Linked	Granulomatous Disease, Chronic, X-Linked, Variant

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07196	KCTD4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	KCTD4	RGD	RGD:1594637
Felis catus	KCTD4	VGNC	VGNC:63063
Mus musculus	KCTD4	MGD	MGI:1914766
Canis familiaris	KCTD4	VGNC	VGNC:42308
Macaca mulatta	KCTD4	VGNC	VGNC:73892
Bos taurus	KCTD4	VGNC	VGNC:30512

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