1. Gene
  2. IL31 - interleukin 31 Gene

IL31 - interleukin 31 Gene

Homo sapiens

Also known as IL-31

Gene ID: 386653 | Gene type: protein coding

About IL31

Cytogenetic location: 12q24.31 Genomic coordinates (GRCh38): 12:122,172,029-122,174,221 (from NCBI)

This gene has 1 transcript (splice variant) and 69 orthologues. Low expression observed in reference dataset.

Summary

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]

IL31 Products(1)

mRNA Protein Name
NM_001014336.2 NP_001014358.1 interleukin-31 precursor

IL31 Protein Structure

IL31

IL31: Interleukin 31 (24 - 159)

  • 0
  • 100
  • 164 a.a.
Protein Preferred Names Protein Names

interleukin-31

Recombinant IL31 Proteins

Cat. No. Product Name Accession Purity
HY-P7217 IL-31 Protein, Human Q6EBC2 (S24-T164) ≥95%
HY-P73209 IL-31 Protein, Human (HEK293, His) Q6EBC2/NP_001014358.1 (S24-T164) ≥95%
HY-P700123AF Animal-Free IL-31 Protein, Human (His) Q6EBC2 (S24-T164) ≥95%

Related Diseases

Diseases Alias
Dermatitis

Eczema

Skin Inflammation

Inflammatory Dermatosis

Allergic Contact Dermatitis

Dermatitis, Allergic Contact

Contact Dermatitis, Allergic

Dermatitis Allergic Contact

Allergic Contact Eczema

Acd - [Allergic Contact Dermatitis]

Allergic Contact Dermatitis, Unspecified Cause

Allergic Dermatitis

Allergic Eczema

Allergy Dermatitis

Allergy Eczema

Allergic Contact Eczema Due To Clothing Or Footwear

Perfume Allergic Contact Dermatitis

Allergic Contact Dermatitis Due To Cosmetics

Allergic Contact Eczema Due To Cosmetics Or Fragrances

Allergic Contact Eczema Due To Dental Materials

Allergic Contact Eczema Due To Food Flavours Or Additives

Allergic Contact Eczema Due To Hairdressing Products

Allergic Contact Eczema Due To Metals Or Metal Salts

Allergic Contact Eczema Due To Proteins

Allergic Contact Eczema Due To Plastics Or Resin Systems

Allergic Contact Eczema Due To Preservatives Or Biocides

Allergic Contact Eczema Due To Rubber Chemicals

Rubber Dermatitis

Allergic Contact Eczema Due To Systemic Medicaments

Allergic Contact Eczema Due To Topical Medicaments

Allergic Contact Dermatitis Due To Drugs In Contact With Skin

Contact Dermatitis

Contact Dermatitis/Eczema

Contact Eczema

Dermatitis Venenata

Dermatitis, Venenata

Dermatitis Contact

Dermatitis, Contact

Primary Cutaneous Amyloidosis

Plca

Primary Localized Cutaneous Amyloidosis

Familial Primary Localized Cutaneous Amyloidosis

Amyloidosis Ix

Lichen Amyloidosis Familial

Amyloidosis, Primary Cutaneous

Pca

Amyloidosis 9

Amyloidosis Familial Cutaneous Lichen

Fplca

Familial Lichen Amyloidosis

Dermatitis, Atopic

Atopic Dermatitis

Atopic Eczema

Dermatitis, Atopic, Susceptibility To, 1

Atod

Eczema, Atopic

Dermatitis, Atopic 1

Allergic Dermatitis

Atopic Neurodermatitis

Besnier'S Prurigo

Dermatitis, Atopic, 1

Dermatitis Atopic

Eczema

Besnier Prurigo

Dermatitis Herpetiformis

Duhring'S Disease

Duhring-Brocq Disease

Dermatosis Herpetiformis

Brocq-Duhring Disease

Dh

Duhring Brocq Disease

Dh - [Dermatitis Herpetiformis]

Mastocytosis, Cutaneous

Urticaria Pigmentosa

Cutaneous Mastocytosis

Diffuse Cutaneous Mastocytosis

Maculopapular Cutaneous Mastocytosis

Mastocytosis, Diffuse Cutaneous

MASTC

Mastocytosis, Maculopapular Cutaneous

Mastocytosis, Systemic, Somatic

Mastocytoma

Dcm

Diffuse Cutaneous Maculopapulous Mastocytosis

Up/Mpcm

Cm

Mastocytosis, Systemic

MASTSYS

Mast Cell Disease

Mast-Cell Disease

Mast Cell Leukemia

Mastocytosis, Indolent

Mastocytosis With Associated Hematologic Disorder

Mast Cell Neoplasm

Benign Mastocytoma

Neurodermatitis
Mite Infestation

Mite Infestations

Acariasis

Infestation By Mites Nos

Chronic Spontaneous Urticaria

Chronic Idiopathic Urticaria

Pemphigoid
Eczema Herpeticum

Herpes Simplex Dermatitis

Herpes Simplex Eyelid Dermatitis

Kaposi Varicelliform Eruption

Herpes Simplex Dermatitis Of Eyelid

Herpes Simplex Virus Dermatitis

Herpes Simplex Virus Eyelid Dermatitis

Urticaria

Nettle Rash

Hives

Wheal

Urticaria Nos

Scabies

Sarcoptic Itch

Infestation By Sarcoptes Scabiei

Infestation By Sarcoptes Scabiei Var Hominis

Infestation By Sarcoptes Scabiei Var. Hominis

Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus

Psoriasis
Irritant Dermatitis

Irritant Contact Dermatitis

Primary Irritant Dermatitis

Dermatitis, Irritant

Contact Dermatitis, Irritant

Irritant Contact Eczema

Icd - [Irritant Contact Dermatitis]

Irritant Contact Dermatitis, Unspecified Cause

Non-Allergic Contact Dermatitis

Irritant Contact Eczema Due To Wet Work

Irritant Contact Dermatitis Due To Detergents

Irritant Contact Eczema Due To Solvents

Irritant Contact Eczema Due To Exposure To Acids, Alkalis Or Other Chemical Irritants

Irritant Contact Eczema Due To Cosmetics Or Emollients

Irritant Contact Eczema Due To Topical Medicaments Or Antimicrobials

Irritant Contact Eczema Due To Plants Or Other Vegetable Matter

Irritant Contact Eczema Due To Foods

Irritant Contact Eczema Due To Friction, Sweating Or Contact With Body Fluids

Irritant Contact Eczema Due To Saliva

Irritant Contact Eczema Due To Incontinence

Incontinence-Associated Dermatitis

Parasitic Ectoparasitic Infectious Disease

Ectoparasitic Infestations

Ectoparasitism

Skin Disease

Skin Diseases

Genodermatosis

Abnormality Of The Skin

Skin Diseases, Genetic

Skin And Subcutaneous Tissue Disease

Dermatologic Disorders

Chronic Inducible Urticaria
Occupational Dermatitis

Dermatitis, Occupational

Occupational Allergic Contact Dermatitis

Occupational Eczema

Chronic Urticaria

Urticaria Chronic

Chronic Spontaneous Urticaria

Chronic Ordinary Urticaria

Fox-Fordyce Disease

Fox Fordyce Disease

Apocrine Miliaria

Fox-Fordyce Syndrome

Miliaria, Apocrine

Skin Atrophy

Atrophic Condition Of Skin

Atrophoderma

Atrophy - Skin

Luminal Breast Carcinoma B

Luminal B Breast Carcinoma

Nasopharyngitis

Chronic Nasopharyngitis

Chronic Rhinopharyngitis

Nasal Cavity Disease

Disorder Of Nasal Cavity

Nose Disease

Nose Diseases

Disorder Of The Nose

Nasal Disorder

Abnormality Of The Nose

Integumentary System Disease
Sezary'S Disease

Sezary Syndrome

Sézary Syndrome

Sezary'S Lymphoma

Sezary Disease

Sezary Erythroderma

Sezary Lymphoma

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus IL31 VGNC VGNC:80444
Canis familiaris IL31 VGNC VGNC:41980
Macaca mulatta IL31 VGNC VGNC:108352
Mus musculus IL31 MGD MGI:1923649
Rattus norvegicus IL31 RGD RGD:1585183
Macaca fascicularis IL31 NCBI NCBI:102135935
Others IL31 NCBI