ONECUT3 - one cut homeobox 3 Gene

Homo sapiens

Also known as OC3

Gene ID: 390874 | Gene type: protein coding

About ONECUT3

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,753,506-1,780,988 (from NCBI)

This gene has 1 transcript (splice variant), 224 orthologues and 2 paralogues. Biased expression in stomach (RPKM 1.8) and duodenum (RPKM 0.1).

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ONECUT3 Products(1)

mRNA	Protein	Name
NM_001080488.2	NP_001073957.1	one cut domain family member 3

ONECUT3 Protein Structure

CUT

Homeobox

0
100
200
300
400
494 a.a.

Protein Preferred Names

Protein Names

one cut domain family member 3

OC-3

ONECUT3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	ONECUT3	O60422	ZMYND12	Homo sapiens	Q9H0C1	Y2H Prey Pooling	32296183
Intra	ONECUT3	O60422	ZMYND12	Homo sapiens	Q9H0C1	Validated Y2H	32296183
Intra	ONECUT3	O60422	ZMYND12	Homo sapiens	Q9H0C1	Y2H Array	32296183
Intra	ONECUT3	O60422	CIB1	Homo sapiens	Q99828	Validated Y2H	32296183
Intra	ONECUT3	O60422	CIB1	Homo sapiens	Q99828	Y2H Prey Pooling	32296183
Intra	ONECUT3	O60422	CIB1	Homo sapiens	Q99828	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Osteogenesis Imperfecta, Type Xvi

Osteogenesis Imperfecta Type 16	OI16
Oi, Type Xvi	Osteogenesis Imperfecta Type Xvi
Chromosome 11p11.2 Deletion Syndrome 91.3-Kb	Osteogenesis Imperfecta 16
Chromosome 11p11.2 Deletion Syndrome, 91.3-Kb

Dracunculiasis

Guinea Worm Disease	Dracontiasis
Dracunculosis	Infection By Dracunculus Medinensis
Gwd	Guinea Worm Infection
Parasitic Infection Caused By Dracunculus Medinensis	Medina Worm Disease
Medinensis	Medina Worm Infestation
Dracunculus Medinensis Infestation	Guinea Worm Infestation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09787	ONECUT3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ONECUT3	RGD	RGD:1591005
Felis catus	ONECUT3	VGNC	VGNC:102652
Mus musculus	ONECUT3	MGD	MGI:1891409
Canis familiaris	ONECUT3	VGNC	VGNC:44124

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