2. Gene
  3. C4b - complement C4B (Chido blood group) Gene

C4b - complement C4B (Chido blood group) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as C4l; C4-2

Gene ID: 406161 | Gene type: protein coding

About C4b

Summary

Predicted to enable carbohydrate binding activity and complement component C1q complex binding activity. Predicted to be involved in complement activation; detection of molecule of Bacterial origin; and positive regulation of apoptotic cell clearance. Predicted to act upstream of or within immunoglobulin mediated immune response. Located in extracellular space. Human ortholog(s) of this gene implicated in autistic disorder; autoimmune disease (multiple); complement component 4b deficiency; and renal cell carcinoma. Orthologous to human C4B (complement C4B (Chido blood group)). [provided by Alliance of Genome Resources, Apr 2022]

C4b Products(1)

mRNA Protein Name
NM_001002805.2 NP_001002805.1 complement component 4, gene 2 precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in extracellular region IDA
IDA: Inferred from direct assay
8805663 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
15634920 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

complement component 4, gene 2

complement C4-like protein

complement component 4B (Chido blood group)

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990091 Riliprubart Inhibitor 99.90% Phase 3
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01746 C4B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99905 Efdamrofusp alfa / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens C4b NCBI NCBI:721
Mus musculus C4b NCBI NCBI:12268