2. Immunology/Inflammation
  3. Complement System
  4. Riliprubart

Riliprubart  (Synonyms: SAR 445088)

Cat. No.: HY-P990091 Purity: 99.90%
SDS COA

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Riliprubart (SAR445088) is an anti-C1s humanized monoclonal antibody that inhibits activated C1s in the proximal portion of the classical complement system. Riliprubart selectively inhibits activated C1s and prevents the enzymatic action of C1 on its substrates C4 and C2, thus inhibiting the formation of the classical pathway C3 convertase, C4b2a.

For research use only. We do not sell to patients.

CAS No. : 2756228-76-7

Size Price Stock Quantity
1 mg USD 140 In-stock
2 mg USD 220 In-stock
5 mg USD 420 In-stock
10 mg USD 670 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

Riliprubart (SAR445088) is an anti-C1s humanized monoclonal antibody that inhibits activated C1s in the proximal portion of the classical complement system. Riliprubart selectively inhibits activated C1s and prevents the enzymatic action of C1 on its substrates C4 and C2, thus inhibiting the formation of the classical pathway C3 convertase, C4b2a[1].

Isotype

Human IgG4 kappa
Recommend Isotype Controls
Species

Chimeric
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Riliprubart]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 kappa
Purity & Documentation

Purity: 99.90%

SDS (251 KB)

COA (231 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Riliprubart Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Riliprubart2756228-76-7SAR 445088SAR445088SAR-445088Complement SystemC1scomplement systemC4C2C3C4b2aInhibitorinhibitorinhibit

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