2. Gene
  3. TM4SF1 - transmembrane 4 L six family member 1 Gene

TM4SF1 - transmembrane 4 L six family member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as L6; H-L6; M3S1; TAAL6

Gene ID: 4071 | Gene type: protein coding

About TM4SF1

Cytogenetic location: 3q25.1 Genomic coordinates (GRCh38): 3:149,369,022-149,377,649 (from NCBI)

This gene has 4 transcripts (splice variants), 116 orthologues and 5 paralogues. Broad expression in gall bladder (RPKM 142.0), lung (RPKM 138.0) and 24 other tissues.

Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008]

TM4SF1 Products(2)

mRNA Protein Name
NM_001410837.1 NP_001397766.1 transmembrane 4 L6 family member 1 isoform 2
NM_014220.3 NP_055035.1 transmembrane 4 L6 family member 1 isoform 1

TM4SF1 Protein Structure

L6_membrane

L6_membrane: L6 membrane protein (1 - 195)

  • 0
  • 100
  • 202 a.a.
Protein Preferred Names Protein Names

transmembrane 4 L6 family member 1

membrane component, chromosome 3, surface marker 1

Recombinant TM4SF1 Proteins

Cat. No. Product Name Accession Purity
HY-P700837 TM4SF1 Protein-VLP, Human (HEK293) P30408 (M1-C202) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-129359 PDP-Pfp 98.66% Unkown
HY-129372 PDdB-Pfp / Unkown
HY-RS14606 TM4SF1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TM4SF1 VGNC VGNC:35903
Macaca mulatta TM4SF1 VGNC VGNC:110328
Rattus norvegicus TM4SF1 RGD RGD:1309652
Canis familiaris TM4SF1 VGNC VGNC:52907
Mus musculus TM4SF1 MGD MGI:104678
Felis catus TM4SF1 VGNC VGNC:66224
Macaca fascicularis TM4SF1 NCBI NCBI:102142030
Others TM4SF1 NCBI