2. Gene
  3. Btla - B and T lymphocyte associated Gene

Btla - B and T lymphocyte associated Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 407756 | Gene type: protein coding

About Btla

Summary

Predicted to enable signaling receptor activity. Predicted to be involved in immune response-regulating cell surface receptor signaling pathway. Predicted to act upstream of or within cell surface receptor signaling pathway; negative regulation of B cell proliferation; and negative regulation of alpha-beta T cell proliferation. Predicted to be located in external side of plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human BTLA (B and T lymphocyte associated). [provided by Alliance of Genome Resources, Apr 2022]

Btla Products(1)

mRNA Protein Name
NM_213630.2 NP_998795.2 B- and T-lymphocyte attenuator precursor
Protein Preferred Names Protein Names

B- and T-lymphocyte attenuator

B- and T-lymphocyte-associated protein

Recombinant Btla Proteins

Cat. No. Product Name Accession Purity
HY-P75466 BTLA/CD272 Protein, Rat (HEK293, mFc) Q6PNM1 (K30-Y183) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99961 Tifcemalimab Inhibitor 95.00% Phase 3
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-159885 MG-B-28 Inhibitor / Unkown
HY-P10851 HVEM(14-39) Inducer / Unkown
HY-RS01669 BTLA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990773 Venanprubart Inhibitor 98.00% Unkown
HY-P991038 Zadoprubart / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Btla NCBI NCBI:151888
Macaca fascicularis Btla NCBI NCBI:102144877
Mus musculus Btla NCBI NCBI:208154
Macaca mulatta Btla NCBI NCBI:708202