MT1F - metallothionein 1F Gene

Homo sapiens

Also known as MT1

Gene ID: 4494 | Gene type: protein coding

About MT1F

Cytogenetic location: 16q13 Genomic coordinates (GRCh38): 16:56,657,959-56,659,303 (from NCBI)

This gene has 4 transcripts (splice variants), 216 orthologues and 11 paralogues. Biased expression in thyroid (RPKM 263.0), kidney (RPKM 198.1) and 9 other tissues.

Summary

Predicted to enable zinc ion binding activity. Involved in cellular response to cadmium ion. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

MT1F Products(2)

mRNA	Protein	Name
NM_001301272.2	NP_001288201.1	metallothionein-1F isoform 2
NM_005949.4	NP_005940.1	metallothionein-1F isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to cadmium ion	IEP IEP: Inferred from expression pattern	16827180	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	8619255	GOA
located in nucleus	IDA IDA: Inferred from direct assay	8619255	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MT1F Protein Structure

Metallothio

0
61 a.a.

Protein Preferred Names

Protein Names

metallothionein-1F

MT-1F

MT1F Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	MT1F	P04733	NOP2	Homo sapiens	P46087	Y2H Array	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Deficiency Anemia

Anemia	Deficiency Anemias
Anaemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08738	MT1F Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MT1F	MGD	MGI:97171
Others	MT1F	NCBI

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