NAP1L3 - nucleosome assembly protein 1 like 3 Gene

Homo sapiens

Also known as MB20; NPL3

Gene ID: 4675 | Gene type: protein coding

About NAP1L3

Cytogenetic location: Xq21.32 Genomic coordinates (GRCh38): X:93,670,930-93,673,578 (from NCBI)

This gene has 2 transcripts (splice variants), 207 orthologues and 18 paralogues.

Summary

This gene is intronless and encodes a member of the nucleosome assembly protein (NAP) family. This gene is linked closely to a region of genes responsible for several X-linked cognitive disability syndromes. [provided by RefSeq, Dec 2010]

NAP1L3 Products(1)

mRNA	Protein	Name
NM_004538.6	NP_004529.2	nucleosome assembly protein 1-like 3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NAP1L3 Protein Structure

NAP

0
100
200
300
400
506 a.a.

Protein Preferred Names

Protein Names

nucleosome assembly protein 1-like 3

NAP1L3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	NAP1L3	Q99457	JPH3	Homo sapiens	Q8WXH2	Validated Y2H	32814053
Intra	NAP1L3	Q99457	JPH3	Homo sapiens	Q8WXH2	Y2H Pooling	32814053
Intra	NAP1L3	Q99457	JPH3	Homo sapiens	Q8WXH2	Y2H Array	32814053
Intra	NAP1L3	Q99457	DNM2	Homo sapiens	P50570-2	Validated Y2H	32814053
Intra	NAP1L3	Q99457	DNM2	Homo sapiens	P50570-2	Y2H Pooling	32814053
Intra	NAP1L3	Q99457	DNM2	Homo sapiens	P50570-2	Y2H Array	32814053
Intra	NAP1L3	Q99457	MECP2	Homo sapiens	P51608	Y2H Pooling	32814053
Intra	NAP1L3	Q99457	MECP2	Homo sapiens	P51608	Validated Y2H	32814053
Intra	NAP1L3	Q99457	MECP2	Homo sapiens	P51608	Y2H Array	32814053
Intra	NAP1L3	Q99457	NAP1L2	Homo sapiens	Q9ULW6	Validated Y2H	32296183
Intra	NAP1L3	Q99457	NDUFV2	Homo sapiens	P19404	Validated Y2H	32814053
Intra	NAP1L3	Q99457	NDUFV2	Homo sapiens	P19404	Y2H Pooling	32814053
Intra	NAP1L3	Q99457	NDUFV2	Homo sapiens	P19404	Y2H Array	32814053
Intra	NAP1L3	Q99457	GFAP	Homo sapiens	P14136	Validated Y2H	32814053
Intra	NAP1L3	Q99457	GFAP	Homo sapiens	P14136	Y2H Array	32814053
Intra	NAP1L3	Q99457	GFAP	Homo sapiens	P14136	Y2H Pooling	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Noonan Syndrome 8

NS8	Noonan Syndrome, Type 8

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09027	NAP1L3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	NAP1L3	VGNC	VGNC:43616
Macaca mulatta	NAP1L3	VGNC	VGNC:75130
Rattus norvegicus	NAP1L3	RGD	RGD:620990
Mus musculus	NAP1L3	MGD	MGI:1859565

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