NINJ1 - ninjurin 1 Gene

Homo sapiens

Also known as NIN1; NINJURIN

Gene ID: 4814 | Gene type: protein coding

About NINJ1

Cytogenetic location: 9q22.31 Genomic coordinates (GRCh38): 9:93,121,496-93,134,251 (from NCBI)

This gene has 5 transcripts (splice variants), 231 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 105.7), placenta (RPKM 42.4) and 24 other tissues.

Summary

The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009]

NINJ1 Products(1)

mRNA	Protein	Name
NM_004148.4	NP_004139.2	ninjurin-1

NINJ1 Protein Structure

Ninjurin

0
100
152 a.a.

Protein Preferred Names

Protein Names

ninjurin-1

nerve injury-induced protein-1

NINJ1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	NINJ1	Q92982	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	25416956
Intra	NINJ1	Q92982	KRT40	Homo sapiens	Q6A162	Validated Y2H	25416956
Intra	NINJ1	Q92982	CYB5R3	Homo sapiens	P00387	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	CYB5R3	Homo sapiens	P00387	Y2H Array	32296183
Intra	NINJ1	Q92982	GPX8	Homo sapiens	Q8TED1	Y2H Array	32296183
Intra	NINJ1	Q92982	GPX8	Homo sapiens	Q8TED1	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	FNDC9	Homo sapiens	Q8TBE3	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	FNDC9	Homo sapiens	Q8TBE3	Y2H Array	32296183
Intra	NINJ1	Q92982	CD200R1	Homo sapiens	Q8TD46-4	Y2H Array	32296183
Intra	NINJ1	Q92982	CD200R1	Homo sapiens	Q8TD46-4	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	CEACAM3	Homo sapiens	P40198	Y2H Array	32296183
Intra	NINJ1	Q92982	CEACAM3	Homo sapiens	P40198	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	TLCD4	Homo sapiens	Q96MV1	Validated Y2H	32296183
Intra	NINJ1	Q92982	TLCD4	Homo sapiens	Q96MV1	Y2H Array	32296183
Intra	NINJ1	Q92982	TLCD4	Homo sapiens	Q96MV1	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	AQP6	Homo sapiens	Q13520	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	AQP6	Homo sapiens	Q13520	Y2H Array	32296183
Intra	NINJ1	Q92982	MUC1	Homo sapiens	P15941-11	Y2H Array	32296183
Intra	NINJ1	Q92982	MUC1	Homo sapiens	P15941-11	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	LIME1	Homo sapiens	Q9H400	Validated Y2H	32296183
Intra	NINJ1	Q92982	LIME1	Homo sapiens	Q9H400	Y2H Array	32296183
Intra	NINJ1	Q92982	LIME1	Homo sapiens	Q9H400	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	FCGR1A	Homo sapiens	P12314	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	FCGR1A	Homo sapiens	P12314	Y2H Array	32296183
Intra	NINJ1	Q92982	EBP	Homo sapiens	Q15125	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	EBP	Homo sapiens	Q15125	Y2H Array	32296183
Intra	NINJ1	Q92982	PVR	Homo sapiens	P15151	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	SGCB	Homo sapiens	Q16585	Y2H Array	32296183
Intra	NINJ1	Q92982	SGCB	Homo sapiens	Q16585	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	TIMMDC1	Homo sapiens	Q9NPL8	Validated Y2H	32296183
Intra	NINJ1	Q92982	TIMMDC1	Homo sapiens	Q9NPL8	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	TIMMDC1	Homo sapiens	Q9NPL8	Y2H Array	32296183
Intra	NINJ1	Q92982	CREB3L1	Homo sapiens	Q96BA8	Y2H Array	32296183
Intra	NINJ1	Q92982	CREB3L1	Homo sapiens	Q96BA8	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	CREB3L1	Homo sapiens	Q96BA8	Validated Y2H	32296183
Intra	NINJ1	Q92982	GOLM1	Homo sapiens	Q8NBJ4	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	GOLM1	Homo sapiens	Q8NBJ4	Y2H Array	32296183
Intra	NINJ1	Q92982	TMEM14B	Homo sapiens	Q9NUH8	Y2H Array	32296183
Intra	NINJ1	Q92982	TMEM14B	Homo sapiens	Q9NUH8	Y2H Prey Pooling	32296183
Intra	NINJ1	Q92982	TMEM14B	Homo sapiens	Q9NUH8	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Spondylometaphyseal Dysplasia With Corneal Dystrophy

SMDCD	Spondylometaphyseal Dysplasia-Corneal Dystrophy Syndrome
Smd-Corneal Dystrophy Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09298	NINJ1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	NINJ1	VGNC	VGNC:43811
Macaca mulatta	NINJ1	VGNC	VGNC:75350
Rattus norvegicus	NINJ1	RGD	RGD:3179
Mus musculus	NINJ1	MGD	MGI:1196617
Bos taurus	NINJ1	VGNC	VGNC:32078
Felis catus	NINJ1	VGNC	VGNC:97527
Others	NINJ1	NCBI

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