2. Gene
  3. Tnfsf14 - tumor necrosis factor (ligand) superfamily, member 14 Gene

Tnfsf14 - tumor necrosis factor (ligand) superfamily, member 14 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as LTg; HVEML; LIGHT; Ly113; HVEM-L; Tnlg1d

Gene ID: 50930 | Gene type: protein coding

About Tnfsf14

Summary

Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process; identical protein binding activity; and signaling receptor binding activity. Acts upstream of or within several processes, including T cell costimulation; positive regulation of T cell chemotaxis; and positive regulation of myoblast fusion. Predicted to be located in plasma membrane. Used to study IgA glomerulonephritis. Orthologous to human TNFSF14 (TNF Superfamily member 14). [provided by Alliance of Genome Resources, Apr 2022]

Tnfsf14 Products(1)

mRNA Protein Name
NM_019418.4 NP_062291.1 tumor necrosis factor ligand superfamily member 14
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
27152329 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of T cell chemotaxis IDA
IDA: Inferred from direct assay
21236258 MGI
acts upstream of or within T cell costimulation IDA
IDA: Inferred from direct assay
15568026 MGI
acts upstream of or within positive regulation of T cell chemotaxis IDA
IDA: Inferred from direct assay
21236258 MGI
acts upstream of or within positive regulation of myoblast differentiation IMP
IMP: Inferred from mutant phenotype
23844157 MGI
acts upstream of or within positive regulation of myoblast fusion IMP
IMP: Inferred from mutant phenotype
23844157 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor necrosis factor ligand superfamily member 14

tumor necrosis factor ligand 1d

Recombinant Tnfsf14 Proteins

Cat. No. Product Name Accession Purity
HY-P73837 LIGHT/TNFSF14 Protein, Mouse (sf9, His) NP_062291.1 (D72-V239) ≥95%
HY-P73837A LIGHT/TNFSF14 Protein, Mouse (sf9, His, solution) Q9QYH9 (D72-V239) ≥95%
HY-P700221AF Animal-Free LIGHT/TNFSF14 Protein, Mouse (His) Q9QYH9 (R58-V239) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99810 Quisovalimab 96.18% Phase 2
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14825 TNFSF14 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfsf14 NCBI NCBI:8740