PCDH7 - protocadherin 7 Gene

Homo sapiens

Also known as BHPCDH; BH-Pcdh; PPP1R120

Gene ID: 5099 | Gene type: protein coding

About PCDH7

Cytogenetic location: 4p15.1 Genomic coordinates (GRCh38): 4:30,720,369-31,146,800 (from NCBI)

This gene has 13 transcripts (splice variants), 206 orthologues and 33 paralogues. Broad expression in brain (RPKM 10.8), spleen (RPKM 5.9) and 17 other tissues.

Summary

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008]

PCDH7 Products(3)

mRNA	Protein	Name
NM_001173523.2	NP_001166994.1	protocadherin-7 isoform d precursor
NM_002589.4	NP_002580.2	protocadherin-7 isoform a precursor
NM_032457.4	NP_115833.2	protocadherin-7 isoform c precursor

PCDH7 Protein Structure

Cadherin_2

Cadherin

Protocadherin

0
200
400
600
800
1000
1069 a.a.

Protein Preferred Names

Protein Names

protocadherin-7

BH-protocadherin (brain-heart)

Recombinant PCDH7 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75956	PCDH7 Protein, Human (sf9, His)	O60245-1/NP_002580.2 (A29-S879)	≥95%

Related Diseases

Diseases

Alias

Astigmatism

Epilepsy, Myoclonic Juvenile

Juvenile Myoclonic Epilepsy	Janz Syndrome
Jme	Myoclonic Epilepsy, Juvenile, Susceptibility To, 1
EJM	Myoclonic Epilepsy, Juvenile
Petit Mal, Impulsive	Myoclonic Epilepsy, Juvenile 1
Myoclonic Epilepsy, Juvenile, 1	Adolescent Myoclonic Epilepsy
Juvenile Myoclonus Epilepsy	Juvenile Myoclonic Epilepsy 1
EJM1	Petit Mal Impulsive
Susceptibility To Juvenile Myoclonic Epilepsy 1	Myoclonic Epilepsy Juvenile
Epilepsy, Myoclonic, Juvenile	Myoclonic Epilepsy Of Janz
Jme - [Juvenile Myoclonic Epilepsy]

Benign Epilepsy With Centrotemporal Spikes

Rolandic Epilepsy	Benign Rolandic Epilepsy
Epilepsy, Rolandic	Bcects
Benign Childhood Epilepsy With Centrotemporal Spike	Sylvan Seizures
Becrs	Bects
Bre	Benign Epilepsy Of Childhood With Centrotemporal Spikes
Benign Familial Epilepsy Of Childhood With Rolandic Spikes	Centrotemporal Epilepsy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10130	PCDH7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	PCDH7	VGNC	VGNC:53195
Macaca mulatta	PCDH7	VGNC	VGNC:75777
Rattus norvegicus	PCDH7	RGD	RGD:1303209
Felis catus	PCDH7	VGNC	VGNC:68717
Mus musculus	PCDH7	MGD	MGI:1860487
Bos taurus	PCDH7	VGNC	VGNC:32621
Others	PCDH7	NCBI

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