YBX2 - Y-box binding protein 2 Gene

Homo sapiens

Also known as DBPC; MSY2; CSDA3; CONTRIN

Gene ID: 51087 | Gene type: protein coding

About YBX2

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,288,263-7,294,639 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 182 orthologues and 4 paralogues. Restricted expression toward testis (RPKM 189.1).

Summary

This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15. [provided by RefSeq, Feb 2012]

YBX2 Products(1)

mRNA	Protein	Name
NM_015982.4	NP_057066.2	Y-box-binding protein 2

YBX2 Protein Structure

CSD

0
100
200
300
364 a.a.

Protein Preferred Names

Protein Names

Y-box-binding protein 2

DNA-binding protein C

Related Diseases

Diseases

Alias

Infertility

Dysgerminoma Of Ovary

Ovarian Dysgerminoma	Malignant Dysgerminomatous Germ Cell Tumour Of Ovary
Dysgerminoma, Unspecified Site, Female

Male Infertility

Infertility, Male	Infertility Male
Male Sterility	Absolute Infertility

Spermatogenic Failure

Azoospermia	Spgf
Spermatogenic Failure, Susceptibility To	Absent Sperm
Aspermatogenesis	Infertility Due To Azoospermia
Hypospermatogenesis	Azoospermatism

Premature Menopause

Primary Ovarian Insufficiency	Premature Ovarian Failure
Hypergonadotropic Hypogonadism	Premature Ovarian Insufficiency
Menopause - Premature	Menopause Praecox
Menopause Premature	Menopause, Premature
Female Hypergonadotropic Hypogonadism	Hypergonadotrophic Ovarian Failure
Primary Female Hypogonadism	Pof - [Premature Ovarian Failure]
Ovarian Failure	Ovarian Secretion Suppression
Ovary Hyposecretion	Ovary Secretion Deficiency
Premature Menopause Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect Pre-designed Sets	Purity	Rare Diseases Unkown
HY-RS15917	YBX2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	YBX2	VGNC	VGNC:99344
Mus musculus	YBX2	MGD	MGI:1096372
Bos taurus	YBX2	VGNC	VGNC:37017
Rattus norvegicus	YBX2	RGD	RGD:1305068
Felis catus	YBX2	VGNC	VGNC:67131

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