IPO11 - importin 11 Gene

Homo sapiens

Also known as RanBP11

Gene ID: 51194 | Gene type: protein coding

About IPO11

Cytogenetic location: 5q12.1 Genomic coordinates (GRCh38): 5:62,412,763-62,628,582 (from NCBI)

This gene has 14 transcripts (splice variants), 202 orthologues and 4 paralogues. Ubiquitous expression in testis (RPKM 13.7), thyroid (RPKM 6.7) and 25 other tissues.

Summary

Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1; 602738) that mediate nucleocytoplasmic transport of protein and RNA cargoes (Plafker and Macara, 2000 [PubMed 11032817]).[supplied by OMIM, Sep 2008]

IPO11 Products(2)

mRNA	Protein	Name
NM_001134779.2	NP_001128251.1	importin-11 isoform 1
NM_016338.5	NP_057422.3	importin-11 isoform 2

IPO11 Protein Structure

IBN_N

0
200
400
600
800
975 a.a.

Protein Preferred Names

Protein Names

importin-11

Ran binding protein 11

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06866	IPO11 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	IPO11	VGNC	VGNC:62953
Canis familiaris	IPO11	VGNC	VGNC:49760
Bos taurus	IPO11	VGNC	VGNC:50068
Macaca mulatta	IPO11	VGNC	VGNC:73633
Mus musculus	IPO11	MGD	MGI:2442377

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