FKBP7 - FKBP prolyl isomerase 7 Gene

Homo sapiens

Also known as FKBP23; PPIase

Gene ID: 51661 | Gene type: protein coding

About FKBP7

Cytogenetic location: 2q31.2 Genomic coordinates (GRCh38): 2:178,463,664-178,478,600 (from NCBI)

This gene has 12 transcripts (splice variants), 210 orthologues and 18 paralogues. Broad expression in ovary (RPKM 13.6), endometrium (RPKM 9.0) and 21 other tissues.

Summary

The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. A similar protein in mouse is located in the endoplasmic reticulum and binds calcium. [provided by RefSeq, Jul 2008]

FKBP7 Products(3)

mRNA	Protein	Name
NM_001135212.2	NP_001128684.1	peptidyl-prolyl cis-trans isomerase FKBP7 isoform b precursor
NM_001410972.1	NP_001397901.1	peptidyl-prolyl cis-trans isomerase FKBP7 isoform c precursor
NM_181342.3	NP_851939.1	peptidyl-prolyl cis-trans isomerase FKBP7 isoform a precursor

FKBP7 Protein Structure

FKBP_C

EF-hand_7

0
100
200
222 a.a.

Protein Preferred Names

Protein Names

peptidyl-prolyl cis-trans isomerase FKBP7

23 kDa FK506-binding protein

FKBP7 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	FKBP7	Q9Y680	NPFFR2	Homo sapiens	Q9Y5X5-3	Y2H Prey Pooling	32296183
Intra	FKBP7	Q9Y680	NPFFR2	Homo sapiens	Q9Y5X5-3	Y2H Array	32296183
Intra	FKBP7	Q9Y680	SGTA	Homo sapiens	O43765	Y2H Prey Pooling	25416956
Intra	FKBP7	Q9Y680	SGTA	Homo sapiens	O43765	Y2H Prey Pooling	32296183
Intra	FKBP7	Q9Y680	SGTA	Homo sapiens	O43765	Y2H Array	32296183
Intra	FKBP7	Q9Y680	PEX19	Homo sapiens	P40855	Y2H Array	25416956
Intra	FKBP7	Q9Y680	TMEM108	Homo sapiens	Q6UXF1	Y2H Array	32296183
Intra	FKBP7	Q9Y680	TMEM108	Homo sapiens	Q6UXF1	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant FKBP7 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70949	FKBP7 Protein, Human (HEK293, His)	Q9Y680-2 (Q24-L222)	≥95%
HY-P76932	FKBP7 Protein, Human (HEK293, Fc)	Q9Y680-2 (Q24-Q218)	≥95%

Related Diseases

Diseases

Alias

Osteogenesis Imperfecta, Type Xi

Osteogenesis Imperfecta Type 11	OI11
Osteogenesis Imperfecta Type Xi	Oi, Type Xi
Osteogenesis Imperfecta 11	Oi Type Xi
Oi-Xi

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04967	FKBP7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	FKBP7	RGD	RGD:1305293
Macaca mulatta	FKBP7	VGNC	VGNC:72667
Felis catus	FKBP7	VGNC	VGNC:62283
Bos taurus	FKBP7	VGNC	VGNC:29026
Mus musculus	FKBP7	MGD	MGI:1336879
Canis familiaris	FKBP7	VGNC	VGNC:40893
Others	FKBP7	NCBI

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